EPPIN

Gene Symbol	EPPIN
Entrez Gene	57119
Alt Symbol	CT71, CT72, SPINLW1, WAP7, WFDC7, dJ461P17.2
Species	Human
Gene Type	protein-coding
Description	epididymal peptidase inhibitor
Other Description	WAP four-disulfide core domain protein 7|cancer/testis antigen 71|cancer/testis antigen 72|epididymal protease inhibitor|eppin|protease inhibitor WAP7|serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
Swissprots	Q86TP9 Q9HD30 A6PVD6 Q96SD7 O95925
Accessions	CAB37635 EAW75831 EAW75832 O95925 AF286368 AAG00546 AF286369 AAG00547 AF286370 AAG00548 AK126022 BAG54278 AK311906 BAG34847 AL118493 CAB56343 BC003675 AAH03675 BC044829 AAH44829 BC053369 AAH53369 BF057305 DA821702 DC395362 HQ448506 ADQ32986 NM_001302861 NP_001289790 NM_020398 NP_065131 NM_181502
Function	Serine protease inhibitor that plays an essential role in male reproduction and fertility. Modulates the hydrolysis of SEMG1 by KLK3/PSA (a serine protease), provides antimicrobial protection for spermatozoa in the ejaculate coagulum, and binds SEMG1 thereby inhibiting sperm motility. {ECO:0000269|PubMed:15229136, ECO:0000269|PubMed:17644992}.
Subcellular Location	Isoform 1: Secreted. Cell surface. Note=Bound to the surface of testicular and on the head and tail of ejaculate spermatozoa.
Tissue Specificity	In testis, expressed and secreted by Sertoli cells, appearing on the surface of testicular and ejaculate spermatozoa. Expressed in the spermatogonia and the earliest preleptotene spermatocytes. In the epididymis, is expressed and secreted by epithelial cells and covers the surface of epididymal spermatozoa and ciliated epithelial cells (at protein level). Expressed specifically in epididymis and testis. Isoform 2 is expressed only in the epididymis. Weak expression is detected in myoid cells as well as spermatogenic cells. {ECO:0000269|PubMed:11404006, ECO:0000269|PubMed:21461566}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Eppin (I-12) - sc-34604 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Eppin (P-13) - sc-34605 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Eppin (H-100) - sc-33817 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Eppin (YY-23) - sc-100726 from Santa Cruz Biotechnology Prices $295.00 Sizes 200 µl ascites Host Mouse Clonality Monoclonal

Anti-SPINLW1 antibody - ab185699 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SPINLW1 / EPPIN Antibody - LS-C192971 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SPINLW1 / EPPIN Antibody - LS-C335205 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

SPINLW1 Antibody (4G3) - H00057119-M02A from Novus Biologicals Prices $349.00 Sizes 200 µl Host Mouse Clonality Monoclonal Clone 4G3

Monoclonal Anti-SPINLW1 antibody produced in mouse - WH0057119M2 from Sigma-Aldrich Prices $347.00 Sizes 200 µl Host Mouse Clonality Monoclonal Clone 4G3

Anti-SPINLW1 antibody produced in rabbit - SAB4300889 from Sigma-Aldrich Prices $230.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

EPPIN Polyclonal Antibody - A2149 from ABclonal Prices $130.00, $220.00, $380.00 Sizes 50 µl, 100 µl, 200 µl Host Rabbit Clonality Polyclonal

SPINLW1 Antibody - abx117229 from Abbexa Host Rabbit Clonality Polyclonal

SPINLW1 Antibody - abx001761 from Abbexa Host Rabbit Clonality Polyclonal

Eppin / SPINLW1 antibody - H00057119-M02A from Acris Antibodies Prices $360.00 Sizes 200 µl Host Mouse Clonality Monoclonal Clone 4G3

Anti-SPINLW1 - 31-B6802 from ARP American Research Products Prices $169.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPINLW1, Polyclonal Antibody - 25-A2149 from ARP American Research Products Prices $299.00, $449.00 Sizes 100 µg, 200 µg Host Rabbit Clonality Polyclonal

Anti-SPINLW1 antibody - STJ25677 from St John's Laboratory Ltd Host Rabbit Clonality Polyclonal

SPINLW1 antibody - 14378-1-AP from Proteintech Group Host Rabbit Clonality Polyclonal

SPINLW1 , Polyclonal Antibody - MBS1488260 from MyBioSource Prices $295.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

SPINLW1 , Polyclonal Antibody - MBS127428 from MyBioSource Prices $230.00, $305.00, $460.00 Sizes 50 µl, 100 µl, 200 µl Host Rabbit Clonality Polyclonal

SPINLW1, Polyclonal Antibody - MBS2530258 from MyBioSource Prices $195.00, $270.00 Sizes 60 µl, 120 µl Host Rabbit Clonality Polyclonal

EPPIN - A2149 from NeoScientific Prices $220.00, $380.00 Sizes 100 µl, 200 µl Host Rabbit Clonality Polyclonal

EPPIN Antibody - 37552 from Signalway Antibody Prices $279.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

SPINLW1 Antibody - 32626 from Signalway Antibody Prices $279.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

SPINLW1 Antibody - E92149 from Enogene Prices $255.00 Sizes 100 µl Host Rabbit

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