Gene Symbol | FBXO31 |
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Entrez Gene | 79791 |
Alt Symbol | FBX14, FBXO14, Fbx31, MRT45, pp2386 |
Species | Human |
Gene Type | protein-coding |
Description | F-box protein 31 |
Other Description | F-box only protein 31|SCF ubiquitin ligase specificity factor|putative breast cancer tumor-suppressor |
Swissprots | Q9UFV4 Q5K680 Q8WYV1 Q96D73 Q5XUX0 |
Accessions | EAW95400 EAW95401 EAW95402 EAW95403 EAW95404 Q5XUX0 AF318348 AAL55855 AF428140 AAQ04213 AK311122 AL117444 CAB55929 AL576585 AY736035 AAU50679 BC002985 BC012748 AAH12748 BE465371 BG718342 BI596608 BI914636 BM151642 BX106211 BX329100 DA493744 DB444853 NM_001282683 NP_001269612 NM_024735 NP_079011 |
Function | Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor. {ECO:0000269|PubMed:16357137, ECO:0000269|PubMed:19412162}. |
Tissue Specificity | Highly expressed in brain. Expressed at moderate levels in most tissues, except bone marrow. {ECO:0000269|PubMed:16357137}. |
FBXO31 (P-14) - sc-164374 from Santa Cruz Biotechnology
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Anti-FBXO31 antibody - ab86137 from Abcam
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Anti-FBXO31 antibody - ab130347 from Abcam
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Anti-FBXO31 antibody - ab68067 from Abcam
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Anti-FBXO31 antibody [1H1] - ab119304 from Abcam
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Anti-FBXO31 antibody - C-terminal - ab198865 from Abcam
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Anti-FBXO31 Antibody (aa310-338, APC) - LS-C235224 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa310-338, AP) - LS-C235222 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa310-338, FITC) - LS-C235225 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa310-338, Biotin) - LS-C235226 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa310-338, PE) - LS-C235229 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa395-444) - LS-C116565 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa431-480) - LS-C111542 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa310-338) - LS-C166084 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa310-338, Azide-free, HRP) - LS-C249974 from LifeSpan Bioscience
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Anti-FBXO31 Antibody - LS-C307969 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa269-368) - LS-C307992 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa309-338) - LS-C321321 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (aa489-539) - LS-C288809 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (clone 1A11) - LS-C173575 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (clone 1H1) - LS-C337553 from LifeSpan Bioscience
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Anti-FBXO31 Antibody (C-Terminus) IHC-plus™ - LS-B10302 from LifeSpan Bioscience
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FBXO31 Antibody - NBP1-19088 from Novus Biologicals
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FBXO31 Antibody - H00079791-B01P from Novus Biologicals
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FBXO31 Antibody - NBP1-46113 from Novus Biologicals
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