FBXO31

Gene Symbol FBXO31
Entrez Gene 79791
Alt Symbol FBX14, FBXO14, Fbx31, MRT45, pp2386
Species Human
Gene Type protein-coding
Description F-box protein 31
Other Description F-box only protein 31|SCF ubiquitin ligase specificity factor|putative breast cancer tumor-suppressor
Swissprots Q9UFV4 Q5K680 Q8WYV1 Q96D73 Q5XUX0
Accessions EAW95400 EAW95401 EAW95402 EAW95403 EAW95404 Q5XUX0 AF318348 AAL55855 AF428140 AAQ04213 AK311122 AL117444 CAB55929 AL576585 AY736035 AAU50679 BC002985 BC012748 AAH12748 BE465371 BG718342 BI596608 BI914636 BM151642 BX106211 BX329100 DA493744 DB444853 NM_001282683 NP_001269612 NM_024735 NP_079011
Function Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor. {ECO:0000269|PubMed:16357137, ECO:0000269|PubMed:19412162}.
Tissue Specificity Highly expressed in brain. Expressed at moderate levels in most tissues, except bone marrow. {ECO:0000269|PubMed:16357137}.

FBXO31 CRISPR/Cas9 KO Plasmid (h) - sc-406474 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO31 HDR Plasmid (h) - sc-406474-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO31 Double Nickase Plasmid (h) - sc-406474-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO31 Double Nickase Plasmid (h2) - sc-406474-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO31 CRISPR Activation Plasmid (h) - sc-406474-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO31 CRISPR Activation Plasmid (h2) - sc-406474-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO31 Lentiviral Activation Particles (h) - sc-406474-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO31 Lentiviral Activation Particles (h2) - sc-406474-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO31 siRNA (h) - sc-93123 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FBXO31 shRNA Plasmid (h) - sc-93123-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FBXO31 shRNA (h) Lentiviral Particles - sc-93123-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN8548 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8548 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10709 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10709

FBXO31 siRNA (Human) - CRJ2566 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FBXO31 - MBS8214876 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FBXO31 (NM_024735.3) - SHH293205 from Creative biogene

Category siRNA
Species Reactivities Human

FBXO31 shRNA Plasmid (Human) - CHJ2566 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FBXO31 miRNA 3'UTR clone - MiUTR3H-10409 from Creative biogene

Species Reactivities Human
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