Gene Symbol | FBXO31 |
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Entrez Gene | 79791 |
Alt Symbol | FBX14, FBXO14, Fbx31, MRT45, pp2386 |
Species | Human |
Gene Type | protein-coding |
Description | F-box protein 31 |
Other Description | F-box only protein 31|SCF ubiquitin ligase specificity factor|putative breast cancer tumor-suppressor |
Swissprots | Q9UFV4 Q5K680 Q8WYV1 Q96D73 Q5XUX0 |
Accessions | EAW95400 EAW95401 EAW95402 EAW95403 EAW95404 Q5XUX0 AF318348 AAL55855 AF428140 AAQ04213 AK311122 AL117444 CAB55929 AL576585 AY736035 AAU50679 BC002985 BC012748 AAH12748 BE465371 BG718342 BI596608 BI914636 BM151642 BX106211 BX329100 DA493744 DB444853 NM_001282683 NP_001269612 NM_024735 NP_079011 |
Function | Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor. {ECO:0000269|PubMed:16357137, ECO:0000269|PubMed:19412162}. |
Tissue Specificity | Highly expressed in brain. Expressed at moderate levels in most tissues, except bone marrow. {ECO:0000269|PubMed:16357137}. |
Human FBXO31 protein fragment - ab132762 from Abcam
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FBXO31-Antibody-Center-Blocking-Peptide - BP17068c from Abgent, a WuXi AppTec company
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FBXO31 blocking peptide - GTX88266-PEP from GeneTex
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FBXO31 Peptide - AC21-1844-P from Abcore
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FBXO31 - H00079791-P01-10 from Acris Antibodies
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FBXO31 - H00079791-P01-25 from Acris Antibodies
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FBXO31 - H00079791-Q01-10 from Acris Antibodies
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FBXO31 - H00079791-Q01-25 from Acris Antibodies
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Recombinant Human FBXO31, His-tagged - FBXO31-28814TH from Creative Biomart
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Recombinant Human F-box only protein 31(FBXO31) - CSB-YP730405HU CSB-EP730405HU CSB-BP730405HU CSB-MP730405HU from Cusabio
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FBXO31 - TP303518 from Acris Antibodies
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FBXO31, Peptide - MBS425670 from MyBioSource
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F-box only protein 31 (FBXO31), Recombinant Protein - MBS1296361 from MyBioSource
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