LDB1

Gene Symbol	LDB1
Entrez Gene	8861
Alt Symbol	CLIM2, NLI
Species	Human
Gene Type	protein-coding
Description	LIM domain binding 1
Other Description	CLIM-2|LDB-1|LIM domain-binding factor CLIM2|LIM domain-binding factor-1|LIM domain-binding protein 1|carboxy terminal LIM domain protein 2|carboxyl-terminal LIM domain-binding protein 2|hLdb1|nuclear LIM interactor
Swissprots	O75479 Q9UGM4 O96010 B4DUC4 Q1EQX1 Q86U70
Accessions	CAB45408 CAB45409 EAW49722 EAW49723 EAW49724 Q86U70 AB016485 BAA31991 AB250384 BAE95402 AF064491 AAC28341 AF068652 AAC77818 AK300588 BAG62286 AK308481 BC000482 AAH00482 BC009246 AAH09246 BT007054 AAP35703 CV575131 DQ890772 ABM81698 DQ893933 ABM84859 XM_005270262 XP_005270319 XM_011540315 XP_011538617 NM_001113407 NP_001106878 NM_003893 NP_003884
Function	Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Expressed in a wide range of adult tissues including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:16815859}.
Top Pathways	Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LDB1 protein fragment - ab152925 from Abcam Category Protein Source Wheat germ Species Human

LDB1 / CLIM2 Antibody Blocking Peptide - LS-E3665 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LDB1 / CLIM2 Antibody Blocking Peptide - LS-E13529 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LDB1 / CLIM2 Antibody Blocking Peptide - LS-E13528 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LDB1-Antibody-C-term-Blocking-Peptide - BP14866b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LDB1 - H00008861-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

LDB1 - H00008861-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

LDB1 fusion protein - ag10082 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant LIM Domain Binding Protein 1 (LDB1) - RPJ524Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant LIM Domain Binding Protein 1 (LDB1) - RPJ524Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human LIM domain-binding protein 1(LDB1) - CSB-YP771433HU CSB-EP771433HU CSB-BP771433HU CSB-MP771433HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

LDB1 Antibody - SH-A13269 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

LDB1 Recombinant Protein (OPCD04879) - OPCD04879 from Aviva Systems Biology Category Protein Source E.coli Species Human

LIM Domain Binding Protein 1, Recombinant Protein - MBS2030582 from MyBioSource Category Protein Prices $185.00, $380.00, $585.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

LIM domain-binding protein 1 (LDB1), Recombinant Protein - MBS1408905 from MyBioSource Category Protein Prices $1,185.00, $1,185.00, $1,405.00, $1,405.00, $1,905.00, $1,905.00, $2,370.00, $2,370.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human LDB1 protein, His & T7-tagged - LDB1-1680H from Creative Biomart Category Protein Source E. coli Species Human

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