Gene Symbol | PFN3 |
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Entrez Gene | 345456 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | profilin 3 |
Other Description | profilin III|profilin-3 |
Swissprots | A2RUL3 P60673 |
Accessions | EAW85006 P60673 AA909745 BC132952 AAI32953 BC132954 AAI32955 NM_001029886 NP_001025057 |
Function | Binds to actin and affects the structure of the cytoskeleton. Slightly reduces actin polymerization. Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P). May be involved in spermatogenesis. {ECO:0000269|PubMed:19419568}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Testis specific. |
Top Pathways | Salmonella infection, Rap1 signaling pathway, Regulation of actin cytoskeleton |
Profilin-3, PFN3, Human, ELISA Kit - E0346h from ARP American Research Products
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profilin 3, ELISA Kit - MBS9338398 from MyBioSource
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Bovine PFN3 ELISA Kit (Custom ELISA) - LS-F14351 from LifeSpan Bioscience
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Human PFN3 ELISA Kit (Custom ELISA) - LS-F14350 from LifeSpan Bioscience
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Human PFN3 ELISA Kit - E030947 from Biobool
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PFN3 ELISA Kit (Human) (OKEH05853) - OKEH05853 from Aviva Systems Biology
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Profilin-3, ELISA Kit - MBS2887054 from MyBioSource
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