Gene Symbol | PFN3 |
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Entrez Gene | 345456 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | profilin 3 |
Other Description | profilin III|profilin-3 |
Swissprots | A2RUL3 P60673 |
Accessions | EAW85006 P60673 AA909745 BC132952 AAI32953 BC132954 AAI32955 NM_001029886 NP_001025057 |
Function | Binds to actin and affects the structure of the cytoskeleton. Slightly reduces actin polymerization. Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P). May be involved in spermatogenesis. {ECO:0000269|PubMed:19419568}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Testis specific. |
Top Pathways | Salmonella infection, Rap1 signaling pathway, Regulation of actin cytoskeleton |
Profilin-3 (D-12) - sc-50957 from Santa Cruz Biotechnology
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Profilin-3 (N-12) - sc-50959 from Santa Cruz Biotechnology
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Anti-PFN3 antibody - ab126502 from Abcam
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Anti-PFN3 antibody produced in rabbit - HPA047234 from Sigma-Aldrich
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Anti-PFN3 (aa 1-62) polyclonal antibody - DPABH-22854 from Creative Diagnostics
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Polyclonal Antibody to Profilin 3 (PFN3) - PAF074Hu01 from Uscn Life Science Inc.
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Polyclonal Antibody to Profilin 3 (PFN3) - PAF074Mu01 from Uscn Life Science Inc.
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Biotin-Linked Antibody to Profilin 3 (PFN3) - PAF074Mu71 from Uscn Life Science Inc.
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FITC-Linked Antibody to Profilin 3 (PFN3) - PAF074Mu81 from Uscn Life Science Inc.
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Profilin 3 Antibody - abx104996 from Abbexa
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Profilin 3, Polyclonal Antibody - MBS2027988 from MyBioSource
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Profilin 3 (PFN3) Polyclonal Antibody - CAU22596 from Biomatik
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Profilin 3 (PFN3), Polyclonal Antibody - MBS2075950 from MyBioSource
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Profilin 3 (PFN3), Polyclonal Antibody - MBS2075951 from MyBioSource
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Profilin 3 (PFN3), Polyclonal Antibody - MBS2075952 from MyBioSource
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Profilin 3 (PFN3), Polyclonal Antibody - MBS2075953 from MyBioSource
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Profilin 3 (PFN3), Polyclonal Antibody - MBS2075954 from MyBioSource
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Profilin 3 (PFN3), Polyclonal Antibody - MBS2075955 from MyBioSource
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