PFN3

Gene Symbol PFN3
Entrez Gene 345456
Alt Symbol -
Species Human
Gene Type protein-coding
Description profilin 3
Other Description profilin III|profilin-3
Swissprots A2RUL3 P60673
Accessions EAW85006 P60673 AA909745 BC132952 AAI32953 BC132954 AAI32955 NM_001029886 NP_001025057
Function Binds to actin and affects the structure of the cytoskeleton. Slightly reduces actin polymerization. Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P). May be involved in spermatogenesis. {ECO:0000269|PubMed:19419568}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000250}.
Tissue Specificity Testis specific.
Top Pathways Salmonella infection, Rap1 signaling pathway, Regulation of actin cytoskeleton

Profilin-3 CRISPR/Cas9 KO Plasmid (h) - sc-410435 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-3 HDR Plasmid (h) - sc-410435-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-3 Double Nickase Plasmid (h) - sc-410435-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-3 Double Nickase Plasmid (h2) - sc-410435-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-3 CRISPR Activation Plasmid (h) - sc-410435-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-3 CRISPR Activation Plasmid (h2) - sc-410435-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-3 Lentiviral Activation Particles (h) - sc-410435-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-3 Lentiviral Activation Particles (h2) - sc-410435-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Profilin-3 siRNA (h) - sc-61407 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Profilin-3 shRNA Plasmid (h) - sc-61407-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Profilin-3 shRNA (h) Lentiviral Particles - sc-61407-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16663 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16663 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PFN3 siRNA (Human) - CRJ7467 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Pfn3 (NM_001029886.2) - SHH374016 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PFN3(NM_001029886.2) - SHR107864 from Creative biogene

Category siRNA
Species Reactivities Human

Human PFN3 siRNA - orb277968 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PFN3 shRNA Plasmid (Human) - CHJ7467 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PFN3 miRNA 3'UTR clone - MiUTR1H-07807 from Creative biogene

Species Reactivities Human
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