EPN1

Gene Symbol EPN1
Entrez Gene 29924
Alt Symbol -
Species Human
Gene Type protein-coding
Description epsin 1
Other Description EH domain-binding mitotic phosphoprotein|EPS-15-interacting protein 1|epsin-1
Swissprots Q9HA18 Q86ST3 Q9Y6I3
Accessions CAE91463 EAW72405 EAW72406 EAW72407 EAW72408 Q9Y6I3 AF073727 AAD38326 AK022454 BAB14041 AK300545 BAG62253 AK314690 BC044651 AAH44651 BU634413 DA657018 HQ257921 ADR82675 XM_005258829 XP_005258886 XM_005258830 XP_005258887 XM_011526880 XP_011525182 XM_011526881 XP_011525183 NM_001130071 NP_001123543 NM_001130072 NP_001123544 NM_013333 NP_037465
Function Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis. {ECO:0000250, ECO:0000269|PubMed:10557078}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Membrane, clathrin-coated pit {ECO:0000250}. Note=Associated with the cytoplasmic membrane at sites where clathrin-coated pits are forming. Colocalizes with clathrin and AP-2 in a punctate pattern on the plasma membrane. Detected in presynaptic nerve terminals and in Golgi stacks. May shuttle to the nucleus when associated with ZBTB16/ZNF145 (By similarity). {ECO:0000250}.
Top Pathways Endocytosis

epsin 1 (B-12) - sc-365914 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
epsin 1 (B-12): sc-365914. Western blot analysis of epsin 1 expression in Jurkat whole cell lysate.

epsin 1 (C-11) - sc-55556 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
epsin 1 (C-11): sc-55556. Western blot analysis of epsin 1 expression in Jurkat (A), NIH/3T3 (B) and C6 (C) whole cell lysates.

epsin 1 (F-7) - sc-55555 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
epsin 1 (F-7): sc-55555. Western blot analysis of epsin 1 expression in Jurkat whole cell lysate.

epsin 1 (G-12) - sc-48372 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
epsin 1 (G-12): sc-48372. Western blot analysis of epsin 1 expression in Jurkat (A), NIH/3T3 (B) and C6 (C) whole cell lysates.

epsin 1 (L-19) - sc-5411 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
epsin 1 (L-19): sc-5411. Western blot analysis of epsin 1 expression in HeLa (A), A-431 (B), K-562 (C) and Jurkat (D) whole cell lysates.

epsin 1 (R-20) - sc-8673 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
epsin 1 (R-20): sc-8673. Indirect, intracellular FCM analysis of fixed and permeabilized Jurkat cells stained with epsin 1 (R-20), followed by PE-conjugated donkey anti-goat IgG: sc-3743. Black line histogram represents the isotype control, normal goat IgG: sc-3887.

epsin 1 (H-130) - sc-25521 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
epsin 1 (H-130): sc-25521. Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate cancer tissue showing luminal membrane staining of tumor cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

epsin 1 (G-11) - sc-55564 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
epsin 1 (G-11): sc-55564. Western blot analysis of epsin 1 expression in Jurkat (A), NIH/3T3 (B) and C6 (C) whole cell lysates.

epsin 1 (A-9) - sc-166354 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
epsin 1 (A-9): sc-166354. Western blot analysis of epsin 1 expression in Jurkat whole cell lysate.

Anti-Epsin 1 antibody - ab192912 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Detection of Epsin 1 by Western Blot of Immunprecipitate.Lane 1: ab192912 at 1 µg/ml labeling Epsin 1 in 293T whole cell lysate immunoprecipitated using ab192912 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).Lane 2: Control IgG.Detection: Chemiluminescence with exposure time of 30 seconds.

Anti-Epsin 1 antibody [EPR3023] - ab75879 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3023
ab75879, at a 1/100 dilution, staining Epsin 1 in SH-SY5Y cells by Immunofluorescence.

Anti-Epsin 1 / EPN1 Antibody (aa203-232, AP) - LS-C256763 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Epsin 1 / EPN1 Antibody (aa203-232, APC) - LS-C256765 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Epsin 1 / EPN1 Antibody (aa203-232, Biotin) - LS-C256766 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Epsin 1 / EPN1 Antibody (aa203-232, FITC) - LS-C256767 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Epsin 1 / EPN1 Antibody (aa203-232, PE) - LS-C256769 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Epsin 1 / EPN1 Antibody (aa203-232, Azide-free, HRP) - LS-C256768 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Epsin 1 / EPN1 Antibody (aa202-232) - LS-C321139 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Epsin 1 / EPN1 Antibody (aa432-481) - LS-C81966 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal lung lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-Epsin 1 / EPN1 Antibody - LS-C155442 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: HeLa 15% SDS PAGE EPN1 / Epsin-1 antibody diluted at 1:500

Anti-Epsin 1 / EPN1 Antibody (aa574-623) - LS-C201640 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human PANC1. EPN1 antibody dilution 1.0 ug/ml.

Anti-Epsin 1 / EPN1 Antibody (aa203-232) - LS-C167791 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
EPN1 Antibody western blot of HeLa cell line lysates (35 ug/lane). The EPN1 antibody detected the EPN1 protein (arrow).

Anti-Epsin 1 / EPN1 Antibody (aa279-437) - LS-C293782 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant Epsin 1 / EPN1.

Epsin 1 Antibody - NBP1-56656 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Epsin 1 Antibody [NBP1-56656] - Titration: 0.2-1 ug/ml, Positive Control: Human Lung.

Epsin 1 Antibody (EPR3023) - NBP1-40602 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3023
Immunocytochemistry/Immunofluorescence: Epsin 1 Antibody (EPR3023) [NBP1-40602] - Immunofluorescent staining of SH-SY5Y cells using anti-Epsin1
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