EPN1

Gene Symbol EPN1
Entrez Gene 29924
Alt Symbol -
Species Human
Gene Type protein-coding
Description epsin 1
Other Description EH domain-binding mitotic phosphoprotein|EPS-15-interacting protein 1|epsin-1
Swissprots Q9HA18 Q86ST3 Q9Y6I3
Accessions CAE91463 EAW72405 EAW72406 EAW72407 EAW72408 Q9Y6I3 AF073727 AAD38326 AK022454 BAB14041 AK300545 BAG62253 AK314690 BC044651 AAH44651 BU634413 DA657018 HQ257921 ADR82675 XM_005258829 XP_005258886 XM_005258830 XP_005258887 XM_011526880 XP_011525182 XM_011526881 XP_011525183 NM_001130071 NP_001123543 NM_001130072 NP_001123544 NM_013333 NP_037465
Function Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis. {ECO:0000250, ECO:0000269|PubMed:10557078}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Membrane, clathrin-coated pit {ECO:0000250}. Note=Associated with the cytoplasmic membrane at sites where clathrin-coated pits are forming. Colocalizes with clathrin and AP-2 in a punctate pattern on the plasma membrane. Detected in presynaptic nerve terminals and in Golgi stacks. May shuttle to the nucleus when associated with ZBTB16/ZNF145 (By similarity). {ECO:0000250}.
Top Pathways Endocytosis

epsin 1 CRISPR/Cas9 KO Plasmid (h) - sc-401566 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

epsin 1 HDR Plasmid (h) - sc-401566-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

epsin 1 Double Nickase Plasmid (h) - sc-401566-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

epsin 1 Double Nickase Plasmid (h2) - sc-401566-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

epsin 1 CRISPR Activation Plasmid (h) - sc-401566-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

epsin 1 CRISPR Activation Plasmid (h2) - sc-401566-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

epsin 1 Lentiviral Activation Particles (h) - sc-401566-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

epsin 1 Lentiviral Activation Particles (h2) - sc-401566-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

epsin 1 siRNA (h) - sc-35323 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

epsin 1 shRNA Plasmid (h) - sc-35323-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

epsin 1 shRNA (h) Lentiviral Particles - sc-35323-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN7926 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7926 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

EPN1 siRNA (Human) - CRH9271 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EPN1 - MBS8209427 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EPN1 (NM_013333.3) - SHH286569 from Creative biogene

Category siRNA
Species Reactivities Human

Human EPN1 siRNA - orb269773 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EPN1 shRNA Plasmid (Human) - CHH9271 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EPN1 miRNA 3'UTR clone - MiUTR3H-09092 from Creative biogene

Species Reactivities Human

EPN1 miRNA 3'UTR clone - MiUTR3H-09093 from Creative biogene

Species Reactivities Human

EPN1 miRNA 3'UTR clone - MiUTR3H-09094 from Creative biogene

Species Reactivities Human
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