EPN1

Gene Symbol	EPN1
Entrez Gene	29924
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	epsin 1
Other Description	EH domain-binding mitotic phosphoprotein|EPS-15-interacting protein 1|epsin-1
Swissprots	Q9HA18 Q86ST3 Q9Y6I3
Accessions	CAE91463 EAW72405 EAW72406 EAW72407 EAW72408 Q9Y6I3 AF073727 AAD38326 AK022454 BAB14041 AK300545 BAG62253 AK314690 BC044651 AAH44651 BU634413 DA657018 HQ257921 ADR82675 XM_005258829 XP_005258886 XM_005258830 XP_005258887 XM_011526880 XP_011525182 XM_011526881 XP_011525183 NM_001130071 NP_001123543 NM_001130072 NP_001123544 NM_013333 NP_037465
Function	Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis. {ECO:0000250, ECO:0000269|PubMed:10557078}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Membrane, clathrin-coated pit {ECO:0000250}. Note=Associated with the cytoplasmic membrane at sites where clathrin-coated pits are forming. Colocalizes with clathrin and AP-2 in a punctate pattern on the plasma membrane. Detected in presynaptic nerve terminals and in Golgi stacks. May shuttle to the nucleus when associated with ZBTB16/ZNF145 (By similarity). {ECO:0000250}.
Top Pathways	Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Epsin 1 full length protein - ab162265 from Abcam Category Protein Source Wheat germ Species Human

Human Epsin 1 protein fragment - ab162266 from Abcam Category Protein Source Wheat germ Species Human

Epsin 1 / EPN1 Antibody Blocking Peptide - LS-E4010 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Epsin 1 / EPN1 Antibody Blocking Peptide - LS-E19816 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Epsin 1 Protein - H00029924-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Epsin 1 Protein - H00029924-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

EPN1-Antibody-Center-Blocking-Peptide - BP16238c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Epsin 1 Blocking Peptide - 33R-1055 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Epsin 1 Protein - abx066455 from Abbexa Category Protein Source E.coli Species Human

Epsin-1 - H00029924-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Epsin-1 - H00029924-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Epsin-1 - H00029924-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Epsin-1 - H00029924-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

EPN1 fusion protein - ag5838 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Epsin 1 (EPN1) - RPJ141Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Epsin 1 (EPN1) - RPJ141Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Epsin-1(EPN1) - CSB-YP896547HU CSB-EP896547HU CSB-BP896547HU CSB-MP896547HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Epsin 1 (EPN1) - RPU141308 from Biomatik Category Protein Prices $235.40, $470.80, $706.20 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

Epsin-1 (transcript variant 3) - TP307099 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

EPN1 Peptide, Human - M34GP05003H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Epsin 1 (EPN1) - RPU41308 from Biomatik Category Protein Prices $188.00, $385.00, $589.00, $701.92 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

EPN1 Recombinant Protein (OPCD02948) - OPCD02948 from Aviva Systems Biology Category Protein Source E.coli Species Human

Epsin 1 Recombinant Protein Antigen - NBP2-56738PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Epsin 1, Recombinant Protein - MBS2031339 from MyBioSource Category Protein Prices $185.00, $385.00, $595.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Epsin-1 (EPN1), Recombinant Protein - MBS1371419 from MyBioSource Category Protein Prices $1,375.00, $1,375.00, $1,595.00, $1,595.00, $2,290.00, $2,290.00, $2,755.00, $2,755.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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