Gene Symbol | FARP1 |
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Entrez Gene | 10160 |
Alt Symbol | CDEP, FARP1-IT1, PLEKHC2, PPP1R75 |
Species | Human |
Gene Type | protein-coding |
Description | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
Other Description | FERM, RhoGEF and pleckstrin domain-containing protein 1|PH domain-containing family C member 2|chondrocyte-derived ezrin-like protein|pleckstrin homology domain-containing family C member 2|protein phosphatase 1, regulatory subunit 75 |
Swissprots | Q5JVI9 Q6IQ29 Q9Y4F1 |
Accessions | EAX08982 Q9Y4F1 AB008430 BAA24267 AI273567 AI274149 AI381545 AK095747 AK123565 AM393180 CAL38058 AM393217 CAL38095 AM393453 CAL38331 AW270133 AW514534 BC041595 AAH41595 BC053593 BC065020 BC071592 AAH71592 BE463494 BM763139 BQ014327 BX115123 CF994038 DB498534 XM_011521046 XP_011519348 NM_001001715 NP_001001715 NM_001286839 NP_001273768 NM_005766 NP_005757 |
Function | Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell junction, synapse, synaptosome {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Note=Recruited to the cell membrane via interaction with CADM1. {ECO:0000250}. |
Tissue Specificity | Detected in cAMP-treated chondrocytes, but not in untreated chondrocytes. Detected in fetal brain, heart and spleen, and in adult testis, kidney and lung. {ECO:0000269|PubMed:9425278}. |
FARP1 (K-20) - sc-74927 from Santa Cruz Biotechnology
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FARP1 (P-18) - sc-74929 from Santa Cruz Biotechnology
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FARP1 (H-300) - sc-98722 from Santa Cruz Biotechnology
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Anti-FARP1 antibody - ab168668 from Abcam
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Anti-FARP1 antibody - ab27494 from Abcam
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Anti-FARP1 antibody - N-terminal - ab173718 from Abcam
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Anti-FARP1 / CDEP Antibody - LS-C3266 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (aa62-90, AP) - LS-C257051 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (aa2-14) - LS-C54634 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (aa62-90, APC) - LS-C257052 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (aa62-90, Biotin) - LS-C257053 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (aa62-90, PE) - LS-C257056 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (aa62-90, FITC) - LS-C257055 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (aa61-90) - LS-C321292 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (aa62-90) - LS-C159622 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (aa62-90, Azide-free, HRP) - LS-C257057 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (N-Terminus) - LS-C205430 from LifeSpan Bioscience
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Anti-FARP1 / CDEP Antibody (aa471-549) - LS-C307480 from LifeSpan Bioscience
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FARP1 Antibody - NBP1-84571 from Novus Biologicals
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FARP1 Antibody (2D4) - H00010160-M01 from Novus Biologicals
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Rabbit Anti-FARP1 Polyclonal Antibody - bs-13144R from Bioss
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FARSLA/CML33 Polyclonal Antibody - bs-13145R from Bioss
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Rabbit Anti-FARP1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13144R-A350 from Bioss
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Rabbit Anti-FARP1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13144R-A488 from Bioss
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Rabbit Anti-FARP1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13144R-A555 from Bioss
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