Gene Symbol | FARP1 |
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Entrez Gene | 10160 |
Alt Symbol | CDEP, FARP1-IT1, PLEKHC2, PPP1R75 |
Species | Human |
Gene Type | protein-coding |
Description | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
Other Description | FERM, RhoGEF and pleckstrin domain-containing protein 1|PH domain-containing family C member 2|chondrocyte-derived ezrin-like protein|pleckstrin homology domain-containing family C member 2|protein phosphatase 1, regulatory subunit 75 |
Swissprots | Q5JVI9 Q6IQ29 Q9Y4F1 |
Accessions | EAX08982 Q9Y4F1 AB008430 BAA24267 AI273567 AI274149 AI381545 AK095747 AK123565 AM393180 CAL38058 AM393217 CAL38095 AM393453 CAL38331 AW270133 AW514534 BC041595 AAH41595 BC053593 BC065020 BC071592 AAH71592 BE463494 BM763139 BQ014327 BX115123 CF994038 DB498534 XM_011521046 XP_011519348 NM_001001715 NP_001001715 NM_001286839 NP_001273768 NM_005766 NP_005757 |
Function | Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Cell junction, synapse, synaptosome {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Note=Recruited to the cell membrane via interaction with CADM1. {ECO:0000250}. |
Tissue Specificity | Detected in cAMP-treated chondrocytes, but not in untreated chondrocytes. Detected in fetal brain, heart and spleen, and in adult testis, kidney and lung. {ECO:0000269|PubMed:9425278}. |
Human FARP1 full length protein - ab132348 from Abcam
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Human FARP1 peptide - ab45554 from Abcam
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Human FARP1 protein fragment - ab160849 from Abcam
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FARP1 / CDEP Antibody Blocking Peptide - LS-E5489 from LifeSpan Bioscience
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FARP1 / CDEP Antibody Blocking Peptide - LS-E25619 from LifeSpan Bioscience
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Recombinant Human FARP1 Protein - H00010160-P01 from Novus Biologicals
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Recombinant Human FARP1 Protein - H00010160-Q01 from Novus Biologicals
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FARP1-Antibody-N-term-Blocking-Peptide - BP18009a from Abgent, a WuXi AppTec company
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FARP1 blocking peptide - GTX89622-PEP from GeneTex
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FARP1 Peptide - AC21-0450-P from Abcore
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FARP1 / CDEP - H00010160-P01-10 from Acris Antibodies
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FARP1 / CDEP - H00010160-P01-25 from Acris Antibodies
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FARP1 / CDEP - H00010160-Q01-10 from Acris Antibodies
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FARP1 / CDEP - H00010160-Q01-25 from Acris Antibodies
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CDEP Peptide - 45-385P from ProSci
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Recombinant Human FERM, RhoGEF and pleckstrin domain-containing protein 1(FARP1) - CSB-YP897492HU CSB-EP897492HU CSB-BP897492HU CSB-MP897492HU from Cusabio
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FARP1 / CDEP (transcript variant 1) - TP308329 from Acris Antibodies
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CDEP/FARP1, Peptide - MBS425425 from MyBioSource
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FARP1 Recombinant Protein Antigen - NBP1-84571PEP from Novus Biologicals
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FARP1 Peptide, Human - M34GP05533H from Creative Peptides
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FERM, RhoGEF and pleckstrin domain-containing protein 1 (FARP1), partial, Recombinant Protein - MBS1465784 from MyBioSource
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FARP1 Immunizing peptide - orb16722 from Biorbyt
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