Gene Symbol | CCL13 |
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Entrez Gene | 6357 |
Alt Symbol | CKb10, MCP-4, NCC-1, NCC1, SCYA13, SCYL1 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 13 |
Other Description | C-C motif chemokine 13|CK-beta-10|monocyte chemoattractant protein 4|monocyte chemotactic protein 4|new CC chemokine 1|small inducible cytokine subfamily A (Cys-Cys), member 13|small-inducible cytokine A13 |
Swissprots | Q99616 Q6ICQ6 O95689 |
Accessions | AAB67307 EAW80205 EAW80206 Q99616 AJ001634 CAA04888 BC008621 AAH08621 BT007385 AAP36049 CR450337 CAG29333 DQ891497 ABM82423 DQ894688 ABM85614 U46767 AAB38703 U59808 AAD09362 X98306 CAA66950 Z77650 CAB01111 Z77651 CAB01112 NM_005408 NP_005399 |
Function | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens. |
Subcellular Location | Secreted. |
Tissue Specificity | Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
Active human MCP4 full length protein - ab191721 from Abcam
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Active MCP4 full length protein - ab9560 from Abcam
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CCL13 / MCP4 Antibody Blocking Peptide - LS-E10733 from LifeSpan Bioscience
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Recombinant Human CCL13/MCP-4 Protein - NBP2-34973 from Novus Biologicals
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CCL13/MCP-4 Recombinant Protein - H00006357-P01 from Novus Biologicals
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CCL13/MCP-4 Recombinant Protein - P3648 from Novus Biologicals
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CCL13/MCP-4 Recombinant Protein - P4425 from Novus Biologicals
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Recombinant Human CCL13/MCP-4 Protein - NBP1-99409 from Novus Biologicals
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Recombinant Human CCL13/MCP-4 Protein - NBP1-48346 from Novus Biologicals
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MCP4 protein - GTX29560 from GeneTex
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MCP4 recombinant protein - GTX65242 from GeneTex
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Recombinant Human CCL13/MCP-4 - 327-P4-025 from R&D Systems
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Recombinant Human CCL13/MCP-4, CF - 327-P4-025/CF from R&D Systems
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CCL13 Protein Lysate (APL10464) - APL10464 from Aviva Systems Biology
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MCP 4 Protein (OPPA00418) - OPPA00418 from Aviva Systems Biology
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MCP 4 Protein (OPPA02478) - OPPA02478 from Aviva Systems Biology
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Recombinant MCP-4 / CCL13 (OPSD00069) - OPSD00069 from Aviva Systems Biology
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Human CCL13 protein - orb168796 from Biorbyt
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Human CCL13 protein (His Tag) - orb80676 from Biorbyt
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CCL13 (His Tag) protein - orb171527 from Biorbyt
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Human CCL13 protein - orb80144 from Biorbyt
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CCL13 Blocking Peptide - 33R-4671 from Fitzgerald
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CCL13 protein (His tag) - 80R-1458 from Fitzgerald
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MCP4 protein - 30R-AM065 from Fitzgerald
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MCP4 protein - 30R-2540 from Fitzgerald
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