TRAP1

Gene Symbol TRAP1
Entrez Gene 10131
Alt Symbol HSP 75, HSP75, HSP90L, TRAP-1
Species Human
Gene Type protein-coding
Description TNF receptor-associated protein 1
Other Description TNFR-associated protein 1|heat shock protein 75 kDa, mitochondrial|tumor necrosis factor type 1 receptor-associated protein
Swissprots Q9UHL5 F5H897 B4DR68 D3DUC8 O75235 O43642 Q12931
Accessions AAC24722 EAW85338 EAW85339 EAW85340 EAW85341 EAW85342 Q12931 AB209805 BAD93042 AF043254 AAC02679 AF154108 AAF15314 AJ890085 CAI64498 AK057620 BAG51942 AK093344 BAC04139 AK223049 BAD96769 AK223076 BAD96796 AK223205 BAD96925 AK299127 BAG61180 BC000406 BC001455 AAH01455 BC002994 BC018950 AAH18950 BC023585 AAH23585 DB452880 DQ893476 ABM84402 DQ896346 ABM87345 JX481354 AFS69159 U12595 AAA87704 XM_011522345 XP_011520647 NM_001272049 NP_001258978 NM_016292 NP_057376
Function Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. {ECO:0000269|PubMed:23525905, ECO:0000269|PubMed:23564345, ECO:0000269|PubMed:23747254}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:23564345}. Mitochondrion inner membrane {ECO:0000269|PubMed:23564345}. Mitochondrion matrix {ECO:0000269|PubMed:23564345}.
Tissue Specificity Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung, placenta and bladder. Expression is higly reduced in bladder cancer and renal cell carcinoma specimens compared to healthy tissues, but it is increased in other type of tumors. {ECO:0000269|PubMed:23564345}.

Heat shock protein 75 kDa, mitochondrial (TRAP1/HSP75), Human, ELISA Kit - CSB-E17179h from ARP American Research Products

Category ELISA Kit
Prices $550.00, $790.00, $791.00, $794.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 0.156 ng/ml
Range 0.625 ng/ml-40 ng/ml

TRAP1 (Human) IP-WB Antibody Pair - H00010131-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

TNF receptor-associated protein 1, ELISA Kit - MBS706000 from MyBioSource

Category ELISA Kit
Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human TRAP1 is typically less than 0.156 ng/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 0.6 25 ng/ml -40 ng/ml.

Human Heat shock protein 75 kDa, mitochondrial (TRAP1/HSP75) ELISA kit - CSB-E17179h from Cusabio

Category ELISA Kit
Sensitivity 0.156 ng/ml
Range 0.625 ng/ml-40 ng/ml

Human TRAP1 ELISA Kit - E038480 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human TRAP1 is typically less than 0.156 ng/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the me

TRAP1 ELISA Kit (Human) (OKCA00688) - OKCA00688 from Aviva Systems Biology

Category ELISA Kit
Prices $655.00
Sizes 96 wells
Sensitivity 0.156 ng/mL
Range 0.625 ng/mL-40 ng/mL

anti-TRAP1 antibody - ARG65737 from Arigo Biolaboratories

Category ELISA Kit

anti-TRAP1 antibody [Trap1-6] - ARG20577 from Arigo Biolaboratories

Category ELISA Kit

anti-TRAP1 antibody [Trap1-6] (Biotin) - ARG20578 from Arigo Biolaboratories

Category ELISA Kit

anti-TRAP1 antibody [Trap1-6] (FITC) - ARG20579 from Arigo Biolaboratories

Category ELISA Kit

anti-TRAP1 antibody [Trap1-6] (RPE) - ARG20580 from Arigo Biolaboratories

Category ELISA Kit

Human Transforming growth factor-beta receptor-associated protein 1 (TGFBRAP1) ELISA Kit - AE17220HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t
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