VPS4B

Gene Symbol VPS4B
Entrez Gene 9525
Alt Symbol MIG1, SKD1, SKD1B, VPS4-2
Species Human
Gene Type protein-coding
Description vacuolar protein sorting 4 homolog B (S. cerevisiae)
Other Description cell migration-inducing 1|cell migration-inducing gene 1 protein|suppressor of K(+) transport growth defect 1|suppressor of K+ transport defect 1|vacuolar protein sorting 4B|vacuolar protein sorting-associated protein 4B
Swissprots Q9GZS7 Q69HW4 O75351
Accessions AAG01471 EAW63143 EAW63144 O75351 AF038960 AAC39874 AF195514 AAG33022 AK290932 BAF83621 AK291253 BAF83942 AK308892 AK309322 AK311041 AY232629 AAP59551 BC009692 AAH09692 BC039574 AAH39574 DA306069 EU831666 ACE87266 EU831748 ACE86582 HQ448561 ADQ33040 XM_006722582 XP_006722645 XM_011526268 XP_011524570 XR_935266 XR_935267 NM_004869 NP_004860
Function Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). {ECO:0000269|PubMed:11563910, ECO:0000269|PubMed:14505570, ECO:0000269|PubMed:18687924}.
Subcellular Location Prevacuolar compartment membrane; Peripheral membrane protein. Late endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Membrane-associated in the prevacuolar endosomal compartment. Localized in HIV-1 particles purified from acutely infected cells.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:11563910}.
Top Pathways Endocytosis

vacuolar protein sorting 4 homolog B (S. cerevisiae) , ELISA Kit - MBS9326031 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 5.0 pg/ml.
Range 31.2 pg/ml - 1000 pg/ml.

Human VPS4B ELISA Kit - E102694 from Biobool

Category ELISA Kit

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9369910 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9354807 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9355971 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9369321 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9356260 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9343950 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9360403 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9367777 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9346977 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9359744 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9363993 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9362328 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9346151 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9345587 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9360766 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9350607 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9377546 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9365371 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9352037 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9368288 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 4B (VPS4B), ELISA Kit - MBS9355051 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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