SOCS2

Gene Symbol	SOCS2
Entrez Gene	8835
Alt Symbol	CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
Species	Human
Gene Type	protein-coding
Description	suppressor of cytokine signaling 2
Other Description	CIS-2|STAT induced STAT inhibitor-2|STAT-induced STAT inhibitor 2|STAT-induced STAT inhibitor-2|cytokine-inducible SH2 protein 2|suppressor of cytokine signaling-2
Swissprots	O14508 O95102 Q9UKS5 O14542 A8K3D1
Accessions	AAD27710 EAW97492 EAW97493 O14508 AB004903 BAA22429 AB006966 BAA22536 AB451318 BAG70132 AF020590 AAC98896 AF037989 AAC34745 AI129818 AK290546 BAF83235 AK297662 BAG60027 AK309452 AK313165 BAG35983 AL161980 AL522912 BC010399 AAH10399 BC070039 BJ996504 CD699665 DA490057 DA709082 DB054162 DB481261 DC300183 XM_005269213 XP_005269270 XM_006719673 XP_006719736 XM_006719674 XP_006719737 XM_011538929 XP_011537231 XM_011538930 XP_011537232 XM_011538931 XP_011537233 XM_011538932 XP_011537234 XM_011538933 XP_011537235 XM_011538934 XP_011537236 XM_011538935 XP_011537237 XM_011538936 XP_011537238 XR_944810 NM_001270467 NP_001257396 NM_001270468 NP_001257397 NM_001270469 NP_001257398 NM_001270470 NP_001257399 NM_001270471 NP_001257400 NM_003877 NP_003868
Function	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Tissue Specificity	High expression in heart, placenta, lung, kidney and prostate.
Top Pathways	Jak-STAT signaling pathway, Insulin signaling pathway, Type II diabetes mellitus, Prolactin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat SOCS2 ELISA Kit (Sandwich ELISA) - LS-F8515 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.124 ng/ml Range 0.313-20 ng/ml

Suppressor of cytokine signaling 2, SOCS2, Human, ELISA Kit - E1415h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 125-8000 pg/mL

Suppressors Of Cytokine Signaling 2 (SOCS2), ELISA Kit - MBS2018897 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.124ng/mL. Range 0.313-20ng/mL

suppressor of cytokine signaling 2, ELISA Kit - MBS9326307 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Suppressors Of Cytokine Signaling 2 (SOCS2) - SEH154Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.124ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Mouse SOCS2 ELISA Kit (Custom ELISA) - LS-F17166 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Bovine SOCS2 ELISA Kit (Custom ELISA) - LS-F17168 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Human SOCS2 ELISA Kit (Custom ELISA) - LS-F17167 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Pig SOCS2 ELISA Kit (Custom ELISA) - LS-F17165 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Rat SOCS2 ELISA Kit (Custom ELISA) - LS-F17169 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Human Suppressor of cytokine signaling 2 ELISA Kit - abx250861 from Abbexa Category ELISA Kit Range 125 pg/ml - 8000 pg/ml

Human Suppressor of cytokine signaling 2 ELISA Kit - EKE52464 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 56 pg/mL Range 125-8000 pg/mL

SOCS2 - EKH3142 from Nordic BioSite Sensitivity 75pg/ml Range 125-8000pg/ml

SOCS2 ELISA Kit (Human) : 96 Wells (OKEH00997) - OKEH00997 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 98 pg/mL Range 125 - 8000 pg/mL

Human SOCS2 ELISA Kit - E036958 from Biobool Category ELISA Kit Sensitivity < 75pg/ml

Human Suppressor of cytokine signaling 2 ELISA Kit - EK3343 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 56pg/mL Range 125-8000 pg/mL

anti-SOCS-2 antibody - ARG53574 from Arigo Biolaboratories Category ELISA Kit

anti-SOCS-2 antibody (Ready-to-Use) - ARG53575 from Arigo Biolaboratories Category ELISA Kit

Suppressor of cytokine signaling 2, ELISA Kit - MBS761249 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 75pg/ml Range 125-8000pg/ml

Suppressor of cytokine signaling 2, ELISA Kit - MBS2883519 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 125-8000 pg/mL

Suppressor of cytokine signaling 2, ELISA Kit - MBS9427177 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Sensitivity Less than 56pg/mL Range 125-8000 pg/mL

Suppressor of cytokine signaling 2, ELISA Kit - MBS765599 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.9pg/ml Range 78-5000pg/ml

Suppressors of Cytokine Signaling 2 (SOCS2), ELISA Kit - MBS9373436 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human SOCS2 ELISA Kit (Sandwich ELISA) - LS-F34940 from LifeSpan Bioscience Category ELISA Kit Sensitivity 75 Range 0.313-20 ng/ml

Mouse SOCS2 ELISA Kit (Sandwich ELISA) - LS-F34942 from LifeSpan Bioscience Category ELISA Kit Sensitivity 46.9 Range 0.313-20 ng/ml

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