SOCS2

Gene Symbol	SOCS2
Entrez Gene	8835
Alt Symbol	CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
Species	Human
Gene Type	protein-coding
Description	suppressor of cytokine signaling 2
Other Description	CIS-2|STAT induced STAT inhibitor-2|STAT-induced STAT inhibitor 2|STAT-induced STAT inhibitor-2|cytokine-inducible SH2 protein 2|suppressor of cytokine signaling-2
Swissprots	O14508 O95102 Q9UKS5 O14542 A8K3D1
Accessions	AAD27710 EAW97492 EAW97493 O14508 AB004903 BAA22429 AB006966 BAA22536 AB451318 BAG70132 AF020590 AAC98896 AF037989 AAC34745 AI129818 AK290546 BAF83235 AK297662 BAG60027 AK309452 AK313165 BAG35983 AL161980 AL522912 BC010399 AAH10399 BC070039 BJ996504 CD699665 DA490057 DA709082 DB054162 DB481261 DC300183 XM_005269213 XP_005269270 XM_006719673 XP_006719736 XM_006719674 XP_006719737 XM_011538929 XP_011537231 XM_011538930 XP_011537232 XM_011538931 XP_011537233 XM_011538932 XP_011537234 XM_011538933 XP_011537235 XM_011538934 XP_011537236 XM_011538935 XP_011537237 XM_011538936 XP_011537238 XR_944810 NM_001270467 NP_001257396 NM_001270468 NP_001257397 NM_001270469 NP_001257398 NM_001270470 NP_001257399 NM_001270471 NP_001257400 NM_003877 NP_003868
Function	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Tissue Specificity	High expression in heart, placenta, lung, kidney and prostate.
Top Pathways	Jak-STAT signaling pathway, Insulin signaling pathway, Type II diabetes mellitus, Prolactin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SOCS2 full length protein - ab131812 from Abcam Category Protein Source Wheat germ Species Human

Human SOCS2 peptide - ab66732 from Abcam Category Peptide

Human SOCS2 protein fragment - ab152922 from Abcam Category Protein Source Wheat germ Species Human

SOCS2 Antibody Blocking Peptide - LS-E23135 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SOCS-2 Protein - H00008835-Q01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human SOCS-2 Protein - H00008835-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

SOCS2 Protein - GTX108602-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

SOCS2 peptide - orb218191 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Dog

SOCS2 Blocking Peptide - abx063522 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog, Pig, Monkey

SOCS2 / CIS2 - H00008835-Q01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

SOCS2 fusion protein - Ag9317 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SOCS2 fusion protein - Ag24394 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET30a Species Human

SOCS2 fusion protein - ag8909 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human SOCS2, His-tagged - SOCS2-2871H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Suppressors Of Cytokine Signaling 2 (SOCS2) - RPH154Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Suppressors Of Cytokine Signaling 2 (SOCS2) - RPH154Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

SOCS2 Blocking Peptide - CBP2328 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Dog, Pig, Monkey

SOCS-2 (E67) Peptide - BS2914P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Suppressors Of Cytokine Signaling 2 (SOCS2) - RPH154Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Suppressor of cytokine signaling 2(SOCS2) - CSB-YP022389HU CSB-EP022389HU CSB-BP022389HU CSB-MP022389HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human SOC2 (SOCS-2), transfected HEK293 cell culture supernatant - 230-20069-200 from RayBiotech Category Protein Prices $110.00 Sizes 200 µl Source Human Embryonic Kidney 293 (HEK293) Cells Species Human

SOCS2 Protein - abx164195 from Abbexa Category Protein Species Human, Mouse, Rat

SOCS2 Peptide, Human - M34GP14875H from Creative Peptides Category Peptide Source Synthetic. Species Human

SOCS2 Blocking Peptide - CBP7420 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Pig

Human SOCS2 protein - orb54308 from Biorbyt Category Protein Prices $289.00, $408.00, $476.00, $765.00, $1,275.00, $2,023.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Human

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