TXNRD3

Gene Symbol TXNRD3
Entrez Gene 114112
Alt Symbol TGR, TR2, TRXR3
Species Human
Gene Type protein-coding
Description thioredoxin reductase 3
Other Description thioredoxin and glutathione reductase|thioredoxin glutathione reductase|thioredoxin reductase 2|thioredoxin reductase TR2
Swissprots Q9NNW6 Q9P101 Q6PIS8 Q86VQ6
Accessions Q86VQ6 AF133519 AAD39929 AF171055 AAD51325 AK299502 BAG61457 BC030028 AAH30028 BC050032 AAH50032 BQ929894 NM_001173513 NP_001166984 NM_052883 NP_443115
Function Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity). {ECO:0000250|UniProtKB:Q99MD6}.
Subcellular Location Cytoplasm {ECO:0000250|UniProtKB:Q99MD6}. Nucleus {ECO:0000250|UniProtKB:Q99MD6}. Microsome {ECO:0000250|UniProtKB:Q99MD6}. Endoplasmic reticulum {ECO:0000250}. Note=Detected in cytoplasm and nucleus in late spermatids. {ECO:0000250|UniProtKB:Q99MD6}.
Top Pathways Selenocompound metabolism, Pyrimidine metabolism

TrxR3 CRISPR/Cas9 KO Plasmid (h) - sc-417361 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TrxR3 HDR Plasmid (h) - sc-417361-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TrxR3 Double Nickase Plasmid (h) - sc-417361-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TrxR3 Double Nickase Plasmid (h2) - sc-417361-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TrxR3 CRISPR Activation Plasmid (h) - sc-417361-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TrxR3 CRISPR Activation Plasmid (h2) - sc-417361-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TrxR3 Lentiviral Activation Particles (h) - sc-417361-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TrxR3 Lentiviral Activation Particles (h2) - sc-417361-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TrxR3 siRNA (h) - sc-106643 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TrxR3 shRNA Plasmid (h) - sc-106643-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TrxR3 shRNA (h) Lentiviral Particles - sc-106643-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TXNRD3 siRNA (Human) - CRJ4349 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TXNRD3 - MBS8201752 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Txnrd3 (NM_001173513.1) - SHH438396 from Creative biogene

Category siRNA
Species Reactivities Human

Human TXNRD3 siRNA - orb274850 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TXNRD3 shRNA Plasmid (Human) - CHJ4349 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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