Gene Symbol | UQCC2 |
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Entrez Gene | 84300 |
Alt Symbol | C6orf125, Cbp6, M19, MNF1, bA6B20.2 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquinol-cytochrome c reductase complex assembly factor 2 |
Other Description | breast cancer-associated protein SGA-81M|cytochrome B protein synthesis 6 homolog|mitochondrial nucleoid factor 1|mitochondrial protein M19|ubiquinol-cytochrome-c reductase complex assembly factor 2 |
Swissprots | Q9BRT2 B2R4I0 |
Accessions | EAX03745 Q9BRT2 AF086234 AI688269 AK127468 AK311835 BAG34777 AY568085 AAS68365 BC006007 AAH06007 BI604191 CB241659 CN261727 DA123098 EF139858 NM_032340 NP_115716 |
Function | Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability. {ECO:0000269|PubMed:22363741, ECO:0000269|PubMed:24385928}. |
Subcellular Location | Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion. Mitochondrion intermembrane space {ECO:0000250}. Mitochondrion matrix {ECO:0000250}. Mitochondrion inner membrane {ECO:0000250}. Note=Predominantly expressed in the mitochondrial inner membrane. {ECO:0000250}. |
Tissue Specificity | Pancreas, skeletal muscle, kidney, liver and heart. {ECO:0000269|PubMed:22363741}. |
C6orf125 (N-17) - sc-245831 from Santa Cruz Biotechnology
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Anti-MNF1 antibody - ab150849 from Abcam
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Anti-MNF1 antibody - C-terminal - ab177829 from Abcam
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Anti-UQCC2 / MNF1 Antibody (C-Terminus) - LS-C170376 from LifeSpan Bioscience
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MNF1 Antibody - NBP2-14240 from Novus Biologicals
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Anti-MNF1 antibody produced in rabbit - HPA039111 from Sigma-Aldrich
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MNF1 Antibody - C-terminal region (ARP69008_P050) - ARP69008_P050 from Aviva Systems Biology
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UQCC2 antibody - 25781-1-AP from Acris Antibodies
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UQCC2 antibody - 25781-1-AP from Proteintech Group
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Anti-UQCC2 (aa 66-126) polyclonal antibody - DPABH-02994 from Creative Diagnostics
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Rabbit Anti-Human UQCC2 Polyclonal Antibody - DPABH-12558 from Creative Diagnostics
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C6orf125 (G-20) - sc-245832 from Santa Cruz Biotechnology
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C6orf125 (P-15) - sc-245833 from Santa Cruz Biotechnology
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Anti-C6orf125 (66-80) antibody produced in rabbit - SAB1103118 from Sigma-Aldrich
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Mouse Anti-Myc Tag Clone Myc.A7/M19 mAb - CSI20567A from Cell Science
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Mouse Anti-Myc Tag Clone Myc.A7/M19 mAb - CSI20567B from Cell Science
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Mouse Anti-Myc Tag Clone Myc.A7/M19 mAb - CSI20567C from Cell Science
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UQCC2 / MNF1 antibody - TA333617 from Acris Antibodies
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MNF1 antibody (FITC) - orb189487 from Biorbyt
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UQCC2 Antibody - abx135906 from Abbexa
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Anti-UQCC2 antibody - STJ112027 from St John's Laboratory Ltd
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UQCC2 Antibody - CSB-PA866268ESR2HU from Cusabio
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UQCC2 Antibody - CSB-PA866268ESR1HU from Cusabio
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UQCC2 - A9986 from NeoScientific
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UQCC2 Polyclonal Antibody - A9986 from ABclonal
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