Gene Symbol | UQCC2 |
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Entrez Gene | 84300 |
Alt Symbol | C6orf125, Cbp6, M19, MNF1, bA6B20.2 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquinol-cytochrome c reductase complex assembly factor 2 |
Other Description | breast cancer-associated protein SGA-81M|cytochrome B protein synthesis 6 homolog|mitochondrial nucleoid factor 1|mitochondrial protein M19|ubiquinol-cytochrome-c reductase complex assembly factor 2 |
Swissprots | Q9BRT2 B2R4I0 |
Accessions | EAX03745 Q9BRT2 AF086234 AI688269 AK127468 AK311835 BAG34777 AY568085 AAS68365 BC006007 AAH06007 BI604191 CB241659 CN261727 DA123098 EF139858 NM_032340 NP_115716 |
Function | Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability. {ECO:0000269|PubMed:22363741, ECO:0000269|PubMed:24385928}. |
Subcellular Location | Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion. Mitochondrion intermembrane space {ECO:0000250}. Mitochondrion matrix {ECO:0000250}. Mitochondrion inner membrane {ECO:0000250}. Note=Predominantly expressed in the mitochondrial inner membrane. {ECO:0000250}. |
Tissue Specificity | Pancreas, skeletal muscle, kidney, liver and heart. {ECO:0000269|PubMed:22363741}. |
UQCC2 / MNF1 Antibody Blocking Peptide - LS-E24747 from LifeSpan Bioscience
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C6orf125 fusion protein - Ag22787 from Proteintech Group
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C6orf125 fusion protein - Ag22710 from Proteintech Group
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Recombinant Human MNF1 - MNF1-1227H from Creative Biomart
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Recombinant Human Mitochondrial nucleoid factor 1(MNF1) - CSB-YP866268HU CSB-EP866268HU CSB-BP866268HU CSB-MP866268HU from Cusabio
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UQCC2 / MNF1 - TP303347 from Acris Antibodies
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MNF1 Recombinant Protein Antigen - NBP2-14240PEP from Novus Biologicals
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MNF1 Peptide, Human - M34GP09620H from Creative Peptides
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Mitochondrial nucleoid factor 1 (MNF1), Recombinant Protein - MBS1441092 from MyBioSource
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