Gene Symbol | DTD1 |
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Entrez Gene | 92675 |
Alt Symbol | C20orf88, DUE-B, DUEB, HARS2, bA379J5.3, bA555E18.1, pqn-68 |
Species | Human |
Gene Type | protein-coding |
Description | D-tyrosyl-tRNA deacylase 1 |
Other Description | D-tyrosyl-tRNA deacylase 1 homolog|D-tyrosyl-tRNA(Tyr) deacylase 1|DNA-unwinding element-binding protein B|histidyl-tRNA synthase-related|histidyl-tRNA synthetase 2 |
Swissprots | Q9H464 Q5W184 Q8WXU8 A8K5X5 Q8TEA8 D3DW37 Q9H474 Q496D1 Q9BW67 |
Accessions | EAX10227 EAX10228 Q8TEA8 AF332356 AAL57046 AK074304 BAB85044 AK291440 BAF84129 BC000599 BC045167 AAH45167 BC100923 AAI00924 BC100924 AAI00925 BC100925 AAI00926 BC100926 AAI00927 BI465352 BU729150 DB550292 HQ447971 ADQ32454 XM_005260871 XP_005260928 XM_005260872 XP_005260929 NM_080820 NP_543010 |
Function | ATPase involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes. May hydrolyze D- tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine. {ECO:0000269|PubMed:15653697, ECO:0000269|PubMed:20065034}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15653697, ECO:0000269|PubMed:20065034}. Cytoplasm {ECO:0000305}. Note=Associated with chromatin at some replication origins containing functional DNA-unwinding elements. |
Tissue Specificity | Expressed in many adult and fetal tissues. Highest levels in testis, ovary, spleen and in adult and fetal brain. {ECO:0000269|PubMed:12392168}. |
DUE-B (P-15) - sc-85552 from Santa Cruz Biotechnology
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Anti-DTD1 antibody - ab122684 from Abcam
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Anti-DTD1 Antibody (C-Terminus) - LS-C152095 from LifeSpan Bioscience
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Anti-DTD1 Antibody (aa137-186) - LS-C152096 from LifeSpan Bioscience
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Anti-DTD1 Antibody (clone 1E1) - LS-C338241 from LifeSpan Bioscience
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HARS2 Antibody (5H2) - NBP2-01425 from Novus Biologicals
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DTD1 Antibody - NBP1-88776 from Novus Biologicals
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HARS2 Antibody - NBP1-81775 from Novus Biologicals
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DTD1 Antibody (1E1) - NBP2-35324 from Novus Biologicals
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DTD1 Antibody - NBP2-35325 from Novus Biologicals
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Anti-DTD1 antibody produced in rabbit - HPA040981 from Sigma-Aldrich
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Anti-DTD1 (56-70) antibody produced in rabbit - SAB1102975 from Sigma-Aldrich
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Anti-DTD1 (111-124) antibody produced in rabbit - SAB1102976 from Sigma-Aldrich
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DTD1 Antibody - C-terminal region (ARP65884_P050) - ARP65884_P050 from Aviva Systems Biology
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DTD1 Antibody - C-terminal region (ARP65885_P050) - ARP65885_P050 from Aviva Systems Biology
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Bombesin Receptor 3 antibody - GTX79490 from GeneTex
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DTD1 Polyclonal Antibody - A5092 from ABclonal
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HARS2 antibody - 70R-17685 from Fitzgerald
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DTD1 antibody - 70R-16942 from Fitzgerald
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DTD1 Antibody - abx003894 from Abbexa
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DTD1 antibody - 17480-1-AP from Acris Antibodies
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Anti-DTD1, Polyclonal Antibody - 25-A5092 from ARP American Research Products
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DTD1 antibody - 17480-1-AP from Proteintech Group
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DTD1 antibody - STJ27083 from St John's Laboratory Ltd
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histidyl-tRNA synthetase 2, Polyclonal Antibody - MBS710675 from MyBioSource
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