Gene Symbol | DTD1 |
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Entrez Gene | 92675 |
Alt Symbol | C20orf88, DUE-B, DUEB, HARS2, bA379J5.3, bA555E18.1, pqn-68 |
Species | Human |
Gene Type | protein-coding |
Description | D-tyrosyl-tRNA deacylase 1 |
Other Description | D-tyrosyl-tRNA deacylase 1 homolog|D-tyrosyl-tRNA(Tyr) deacylase 1|DNA-unwinding element-binding protein B|histidyl-tRNA synthase-related|histidyl-tRNA synthetase 2 |
Swissprots | Q9H464 Q5W184 Q8WXU8 A8K5X5 Q8TEA8 D3DW37 Q9H474 Q496D1 Q9BW67 |
Accessions | EAX10227 EAX10228 Q8TEA8 AF332356 AAL57046 AK074304 BAB85044 AK291440 BAF84129 BC000599 BC045167 AAH45167 BC100923 AAI00924 BC100924 AAI00925 BC100925 AAI00926 BC100926 AAI00927 BI465352 BU729150 DB550292 HQ447971 ADQ32454 XM_005260871 XP_005260928 XM_005260872 XP_005260929 NM_080820 NP_543010 |
Function | ATPase involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes. May hydrolyze D- tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine. {ECO:0000269|PubMed:15653697, ECO:0000269|PubMed:20065034}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15653697, ECO:0000269|PubMed:20065034}. Cytoplasm {ECO:0000305}. Note=Associated with chromatin at some replication origins containing functional DNA-unwinding elements. |
Tissue Specificity | Expressed in many adult and fetal tissues. Highest levels in testis, ovary, spleen and in adult and fetal brain. {ECO:0000269|PubMed:12392168}. |
Human DTD1 full length protein - ab137172 from Abcam
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DTD1 Antibody Blocking Peptide - LS-E23973 from LifeSpan Bioscience
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DTD1 Antibody Blocking Peptide - LS-E23974 from LifeSpan Bioscience
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HARS2 Antibody Blocking Peptide - LS-E22864 from LifeSpan Bioscience
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HARS2 Antibody Blocking Peptide - LS-E22865 from LifeSpan Bioscience
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Recombinant Human HARS2 Protein - H00023438-Q01 from Novus Biologicals
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DTD1 Recombinant Protein - H00092675-P01 from Novus Biologicals
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Recombinant Human DTD1 Protein - NBP2-23008 from Novus Biologicals
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HARS2 Peptide - P2596 from Novus Biologicals
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HARS2 Peptide - P2595 from Novus Biologicals
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DTD1-Antibody-C-term-Blocking-Peptide - BP8922b from Abgent, a WuXi AppTec company
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Human DTD1 Enzyme - orb191402 from Biorbyt
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DTD1 protein (His tag) - 80R-2609 from Fitzgerald
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DTD1 (1-209, His-tag) - AR50655PU-N from Acris Antibodies
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DTD1 (1-209, His-tag) - AR50655PU-S from Acris Antibodies
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DTD1 - H00092675-P01-10 from Acris Antibodies
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DTD1 - H00092675-P01-25 from Acris Antibodies
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DTD1, 1-209aa, Human, His tag, E.coli - 01-P1831 from ARP American Research Products
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DTD1 fusion protein - Ag11510 from Proteintech Group
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DTD1 fusion protein - Ag11634 from Proteintech Group
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Recombinant Human DTD1, GST-tagged - DTD1-12185H from Creative Biomart
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Recombinant Human D-tyrosyl-tRNA deacylase 1, His-tagged - DTD1-392H from Creative Biomart
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Recombinant Human D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) - CSB-YP819477HU CSB-EP819477HU CSB-BP819477HU CSB-MP819477HU from Cusabio
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DTD1, 1-209aa, Human, His tag, E.coli - ATGP1831 from ATGen
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