Gene Symbol | NUB1 |
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Entrez Gene | 51667 |
Alt Symbol | BS4, NUB1L, NYREN18 |
Species | Human |
Gene Type | protein-coding |
Description | negative regulator of ubiquitin-like proteins 1 |
Other Description | NEDD8 ultimate buster 1|NEDD8 ultimate buster-1|renal carcinoma antigen NY-REN-18 |
Swissprots | Q8IX22 Q75MR9 O95422 Q9BXR2 Q9Y5A7 |
Accessions | AAC82474 AAS02030 EAL24511 EAW54000 EAW54001 EAW54002 EAW54003 Q9Y5A7 AF155099 AAD42865 AF300717 AAK21001 AF459743 AAO14547 AK026433 AK293159 BAH11464 AW205479 AY129295 AAN01355 BC034716 BC046354 AAH46354 BG105733 CN258712 DB048887 XM_005250011 XP_005250068 XM_011516302 XP_011514604 XM_011516303 XP_011514605 XM_011516304 XP_011514606 XM_011516305 XP_011514607 NM_001243351 NP_001230280 NM_016118 NP_057202 |
Function | Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. {ECO:0000269|PubMed:16707496}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11259415}. Note=Predominantly nuclear. |
Tissue Specificity | Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2. |
NUB1 Antibody - 14810 from Cell Signaling Technology
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NUB1 (F-10) - sc-377003 from Santa Cruz Biotechnology
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NUB1 (C-13) - sc-48059 from Santa Cruz Biotechnology
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NUB1 (Y-14) - sc-48062 from Santa Cruz Biotechnology
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NUB1 (H-71) - sc-134516 from Santa Cruz Biotechnology
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Anti-NYREN18 antibody - ab38438 from Abcam
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Anti-NYREN18 antibody - ab169454 from Abcam
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Anti-NYREN18 antibody - ab38437 from Abcam
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Anti-NYREN18 antibody - ab58401 from Abcam
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Anti-NYREN18 antibody [2G1] - ab131600 from Abcam
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Anti-NYREN18 antibody [4H2] - ab128096 from Abcam
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Anti-NYREN18 antibody [EPR10716] - ab171077 from Abcam
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Anti-NYREN18 antibody [EPR10717] - ab178414 from Abcam
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Anti-NYREN18 antibody - C-terminal - ab157163 from Abcam
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Anti-NUB1 Antibody (C-Terminus, AP) - LS-C280340 from LifeSpan Bioscience
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Anti-NUB1 Antibody (C-Terminus, APC) - LS-C280341 from LifeSpan Bioscience
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Anti-NUB1 Antibody (C-Terminus, Biotin) - LS-C280343 from LifeSpan Bioscience
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Anti-NUB1 Antibody (C-Terminus, FITC) - LS-C280344 from LifeSpan Bioscience
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Anti-NUB1 Antibody (C-Terminus, Azide-free, HRP) - LS-C280345 from LifeSpan Bioscience
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Anti-NUB1 Antibody (N-Terminus, AP) - LS-C280346 from LifeSpan Bioscience
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Anti-NUB1 Antibody (C-Terminus, PE) - LS-C280348 from LifeSpan Bioscience
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Anti-NUB1 Antibody (N-Terminus, APC) - LS-C280347 from LifeSpan Bioscience
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Anti-NUB1 Antibody (N-Terminus, Biotin) - LS-C280349 from LifeSpan Bioscience
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Anti-NUB1 Antibody (aa566-615) - LS-C118607 from LifeSpan Bioscience
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Anti-NUB1 Antibody (N-Terminus, FITC) - LS-C280350 from LifeSpan Bioscience
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