Gene Symbol | NUB1 |
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Entrez Gene | 51667 |
Alt Symbol | BS4, NUB1L, NYREN18 |
Species | Human |
Gene Type | protein-coding |
Description | negative regulator of ubiquitin-like proteins 1 |
Other Description | NEDD8 ultimate buster 1|NEDD8 ultimate buster-1|renal carcinoma antigen NY-REN-18 |
Swissprots | Q8IX22 Q75MR9 O95422 Q9BXR2 Q9Y5A7 |
Accessions | AAC82474 AAS02030 EAL24511 EAW54000 EAW54001 EAW54002 EAW54003 Q9Y5A7 AF155099 AAD42865 AF300717 AAK21001 AF459743 AAO14547 AK026433 AK293159 BAH11464 AW205479 AY129295 AAN01355 BC034716 BC046354 AAH46354 BG105733 CN258712 DB048887 XM_005250011 XP_005250068 XM_011516302 XP_011514604 XM_011516303 XP_011514605 XM_011516304 XP_011514606 XM_011516305 XP_011514607 NM_001243351 NP_001230280 NM_016118 NP_057202 |
Function | Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. {ECO:0000269|PubMed:16707496}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11259415}. Note=Predominantly nuclear. |
Tissue Specificity | Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2. |
Human NYREN18 full length protein - ab162630 from Abcam
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Human NYREN18 protein fragment - ab162631 from Abcam
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NUB1 Antibody Blocking Peptide - LS-E6972 from LifeSpan Bioscience
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NUB1 Antibody Blocking Peptide - LS-E6973 from LifeSpan Bioscience
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NUB1/NYREN18 Recombinant Protein - H00051667-P01 from Novus Biologicals
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Recombinant Human NUB1/NYREN18 Protein - H00051667-Q01 from Novus Biologicals
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NUB1/NYREN18 Peptide - P1116 from Novus Biologicals
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NUB1/NYREN18 Peptide - P1115 from Novus Biologicals
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NYREN18-Antibody-C-term-Blocking-Peptide - BP2510b from Abgent, a WuXi AppTec company
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NYREN18-Antibody-N-term-Blocking-Peptide - BP2510a from Abgent, a WuXi AppTec company
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NUB1 Blocking Peptide - abx063873 from Abbexa
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NUB1 - H00051667-P01-10 from Acris Antibodies
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NUB1 - H00051667-P01-25 from Acris Antibodies
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NUB1 - H00051667-Q01-10 from Acris Antibodies
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NUB1 - H00051667-Q01-25 from Acris Antibodies
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NUB1 fusion protein - Ag5668 from Proteintech Group
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Human NYREN18 Antibody - GWB-ASD225 from Genway Biotech
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Recombinant Human NUB1, His-tagged - NUB1-1391H from Creative Biomart
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Recombinant Human NUB1 - NUB1-866H from Creative Biomart
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NUB1 Blocking Peptide - CBP2679 from Cohesion Biosciences
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NUB1 (Y601) Peptide - BS1464P from Bioworld Technology
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Recombinant Human NEDD8 ultimate buster 1(NUB1) - CSB-YP897560HU CSB-EP897560HU CSB-BP897560HU CSB-MP897560HU from Cusabio
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NUB1 - TP308098 from Acris Antibodies
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NUB1/NYREN18 Recombinant Protein Antigen - NBP2-48553PEP from Novus Biologicals
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NUB1 Peptide, Human - M34GP10690H from Creative Peptides
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