PJA2

Gene Symbol PJA2
Entrez Gene 9867
Alt Symbol Neurodap1, RNF131
Species Human
Gene Type protein-coding
Description praja ring finger 2, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase Praja-2|praja 2, RING-H2 motif containing|praja2|ring finger protein 131
Swissprots Q68D49 D3DSZ5 O43164 Q8N1G5 A8K6U4
Accessions EAW49050 EAW49051 O43164 AB007898 BAA23710 AK291759 BAF84448 BC030826 AAH30826 BM469517 BM681899 BP301854 BQ228553 CR749579 CAH18371 NM_014819 NP_055634
Function Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes. {ECO:0000269|PubMed:12036302, ECO:0000269|PubMed:21423175}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21423175}. Cell membrane {ECO:0000269|PubMed:21423175}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:21423175}; Peripheral membrane protein {ECO:0000269|PubMed:21423175}. Golgi apparatus membrane {ECO:0000269|PubMed:21423175}; Peripheral membrane protein {ECO:0000269|PubMed:21423175}. Cell junction, synapse {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Note=Localizes at the cytoplasmic side of endoplasmic reticulum and Golgi apparatus. Expressed in the postsynaptic density region of synapses (By similarity). Colocalizes with PRKAR2A and PRKAR2B in the cytoplasm and the cell membrane. {ECO:0000250}.

PJA2 (H-4) - sc-390137 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PJA2 (H-4): sc-390137. Western blot analysis of PJA2 expression in Jurkat (A) and IMR-32 (B) whole cell lysates.

PJA2 (A-4) - sc-390165 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PJA2 (A-4): sc-390165. Western blot analysis of PJA2 expression in Jurkat (A) and IMR-32 (B) whole cell lysates.

PJA2 (N-17) - sc-243803 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PJA2 (N-17): sc-243803. Western blot analysis of PJA2 expression in Jurkat (A) and IMR-32 (B) whole cell lysates and mouse brain tissue extract (C).

PJA2 (S-20) - sc-243804 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PJA2 antibody - ab131118 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney glomeruli staining PJA2 with ab131118 at 10 µg/ml.

Anti-PJA2 antibody - ab56876 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56876 PJA2 antibody at 1ug/ml.

Anti-PJA2 antibody - ab92734 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PJA2 antibody (ab92734) at 1/500 dilutionLane 1 : Extracts from Jurkat cells minus immunising peptide 10ugLane 2 : Extracts from Jurkat cells plus immunising peptide 10ugLysates/proteins at 30 µg per lane.

Anti-PJA2 antibody - ab130598 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PJA2 antibody (ab130598) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

Anti-PJA2 antibody - ab125330 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PJA2 antibody (ab125330) at 1 µg/ml + Mouse heart lysate at 10 µg

Anti-PJA2 Antibody (aa284-311, Biotin) - LS-C266403 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PJA2 Antibody (aa284-311, AP) - LS-C266401 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PJA2 Antibody (aa284-311, APC) - LS-C266402 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PJA2 Antibody (aa284-311, FITC) - LS-C266404 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PJA2 Antibody (aa284-311, Azide-free, HRP) - LS-C266405 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PJA2 Antibody (aa284-311, PE) - LS-C266406 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PJA2 Antibody (aa200-250) - LS-C289699 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PJA2 Antibody (aa150-200) - LS-C289697 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PJA2 Antibody (aa283-311) - LS-C324062 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PJA2 Antibody - LS-C334723 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of U2OS cell using PJA2 antibody. Blue: DAPI for nuclear staining.

Anti-PJA2 Antibody (aa284-311) - LS-C158665 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PJA2 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The PJA2 antibody detected the PJA2 protein (arrow).

Anti-PJA2 Antibody (aa141-190) IHC-plus™ - LS-B6589 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PJA2 antibody IHC of human kidney, glomeruli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6589 concentration 10 ug/ml.

Anti-PJA2 Antibody (aa24-73) IHC-plus™ - LS-B11129 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PJA2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11129 concentration 10 ug/ml.

PJA2/Praja2 Antibody - NBP1-83006 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PJA2/Praja2 Antibody [NBP1-83006] - Immunofluorescent staining of human cell line U-2 OS shows localization to intermediate filaments.

PJA2/Praja2 Antibody - H00009867-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PJA2/Praja2 Antibody [H00009867-A01] - PJA2 polyclonal antibody (A01), Lot # 051221JC01 Western Blot analysis of PJA2 expression in HL-60 ( Cat # L014V1 ).

PJA2/Praja2 Antibody (1G11) - H00009867-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G11
Western Blot: PJA2/Praja2 Antibody (1G11) [H00009867-M01] - Analysis of PJA2 expression in transfected 293T cell line by PJA2 monoclonal antibody (M01), clone 1G11.Lane 1: PJA2 transfected lysate (Predicted MW: 78.2 KDa).Lane 2: Non-transfected lysate.
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