PJA2

Gene Symbol	PJA2
Entrez Gene	9867
Alt Symbol	Neurodap1, RNF131
Species	Human
Gene Type	protein-coding
Description	praja ring finger 2, E3 ubiquitin protein ligase
Other Description	E3 ubiquitin-protein ligase Praja-2|praja 2, RING-H2 motif containing|praja2|ring finger protein 131
Swissprots	Q68D49 D3DSZ5 O43164 Q8N1G5 A8K6U4
Accessions	EAW49050 EAW49051 O43164 AB007898 BAA23710 AK291759 BAF84448 BC030826 AAH30826 BM469517 BM681899 BP301854 BQ228553 CR749579 CAH18371 NM_014819 NP_055634
Function	Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes. {ECO:0000269|PubMed:12036302, ECO:0000269|PubMed:21423175}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:21423175}. Cell membrane {ECO:0000269|PubMed:21423175}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:21423175}; Peripheral membrane protein {ECO:0000269|PubMed:21423175}. Golgi apparatus membrane {ECO:0000269|PubMed:21423175}; Peripheral membrane protein {ECO:0000269|PubMed:21423175}. Cell junction, synapse {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Note=Localizes at the cytoplasmic side of endoplasmic reticulum and Golgi apparatus. Expressed in the postsynaptic density region of synapses (By similarity). Colocalizes with PRKAR2A and PRKAR2B in the cytoplasm and the cell membrane. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PJA2 full length protein - ab132619 from Abcam Category Protein Source Wheat germ Species Human

PJA2 protein (His-DHFR tag) - ab127672 from Abcam Category Protein Source E. coli Species Human

PJA2 Antibody Blocking Peptide - LS-E4840 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PJA2/Praja2 Protein - H00009867-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PJA2/Praja2 Protein - H00009867-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PJA2-Antibody-Center-Blocking-Peptide - BP17220c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PJA2 peptide - orb218293 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human

Praja2 Blocking Peptide - abx063624 from Abbexa Category Peptide Species Human

PJA2 / RNF131 - H00009867-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PJA2 / RNF131 - H00009867-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PJA2 / RNF131 - H00009867-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PJA2 / RNF131 - H00009867-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PJA2 fusion protein - ag3434 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Praja2 Blocking Peptide - CBP2430 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

Recombinant Human E3 ubiquitin-protein ligase Praja-2(PJA2) - CSB-YP018050HU CSB-EP018050HU CSB-BP018050HU CSB-MP018050HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PJA2/Praja2 Recombinant Protein Antigen - NBP1-83006PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PJA2 Peptide, Human - M34GP11833H from Creative Peptides Category Peptide Source Synthetic. Species Human

PJA2/Praja2 Recombinant Protein Antigen - NBP2-56901PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

E3 ubiquitin-protein ligase Praja-2 (PJA2), Recombinant Protein - MBS1202004 from MyBioSource Category Protein Prices $1,515.00, $1,515.00, $1,740.00, $1,740.00, $2,595.00, $2,595.00, $3,035.00, $3,035.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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