PJA2

Gene Symbol PJA2
Entrez Gene 9867
Alt Symbol Neurodap1, RNF131
Species Human
Gene Type protein-coding
Description praja ring finger 2, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase Praja-2|praja 2, RING-H2 motif containing|praja2|ring finger protein 131
Swissprots Q68D49 D3DSZ5 O43164 Q8N1G5 A8K6U4
Accessions EAW49050 EAW49051 O43164 AB007898 BAA23710 AK291759 BAF84448 BC030826 AAH30826 BM469517 BM681899 BP301854 BQ228553 CR749579 CAH18371 NM_014819 NP_055634
Function Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes. {ECO:0000269|PubMed:12036302, ECO:0000269|PubMed:21423175}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21423175}. Cell membrane {ECO:0000269|PubMed:21423175}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:21423175}; Peripheral membrane protein {ECO:0000269|PubMed:21423175}. Golgi apparatus membrane {ECO:0000269|PubMed:21423175}; Peripheral membrane protein {ECO:0000269|PubMed:21423175}. Cell junction, synapse {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Note=Localizes at the cytoplasmic side of endoplasmic reticulum and Golgi apparatus. Expressed in the postsynaptic density region of synapses (By similarity). Colocalizes with PRKAR2A and PRKAR2B in the cytoplasm and the cell membrane. {ECO:0000250}.

PJA2 CRISPR/Cas9 KO Plasmid (h) - sc-405742 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PJA2 HDR Plasmid (h) - sc-405742-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PJA2 Double Nickase Plasmid (h) - sc-405742-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PJA2 Double Nickase Plasmid (h2) - sc-405742-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PJA2 CRISPR Activation Plasmid (h) - sc-405742-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PJA2 CRISPR Activation Plasmid (h2) - sc-405742-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PJA2 Lentiviral Activation Particles (h) - sc-405742-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PJA2 Lentiviral Activation Particles (h2) - sc-405742-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PJA2 siRNA (h) - sc-91836 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PJA2 shRNA Plasmid (h) - sc-91836-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PJA2 shRNA (h) Lentiviral Particles - sc-91836-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PJA2/Praja2 RNAi - H00009867-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU141761 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16852 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16852 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PJA2 siRNA (Human) - CRH6616 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PJA2 (NM_014819.4) - SHH376332 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PJA2(NM_014819.4) - SHR116880 from Creative biogene

Category siRNA
Species Reactivities Human

Human PJA2 siRNA - orb267118 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PJA2 shRNA Plasmid (Human) - CHH6616 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PJA2 miRNA 3'UTR clone - MiUTR1H-07936 from Creative biogene

Species Reactivities Human
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