TRIM72

Gene Symbol	TRIM72
Entrez Gene	493829
Alt Symbol	MG53
Species	Human
Gene Type	protein-coding
Description	tripartite motif containing 72, E3 ubiquitin protein ligase
Other Description	mitsugumin 53|mitsugumin-53|tripartite motif-containing 72|tripartite motif-containing protein 72
Swissprots	Q8NBD9 Q8N4X6 Q6ZMU5
Accessions	EAW52145 EAW52146 Q6ZMU5 AK090695 BAC03506 AK131485 BAD18630 BC033211 AAH33211 DA058421 DA821604 NM_001008274 NP_001008275
Function	Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane, sarcolemma {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}. Note=Tethered to plasma membrane and cytoplasmic vesicles via its interaction with phosphatidylserine. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Tripartite motif-containing protein 72 (TRIM72), Human, ELISA Kit - CSB-EL024511HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Tripartite motif-containing protein 72, TRIM72, Human, ELISA Kit - E3671h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

TRIM72 (Human) IP-WB Antibody Pair - H00493829-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

TRIM72 (Human) IP-WB Antibody Pair - H00493829-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

TRIM72 (Human) IP-WB Antibody Pair - H00493829-PW3 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

TRIM72 (Human) IP-WB Antibody Pair - H00493829-PW4 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

tripartite motif-containing 72, ELISA Kit - MBS943592 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human TRIM72 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 25 pg/ml-1600 pg/ml.

Human Tripartite motif-containing protein 72(TRIM72) ELISA kit - CSB-EL024511HU from Cusabio Category ELISA Kit Sensitivity 6.25 pg/ml Range 25 pg/ml-1600 pg/ml

Rabbit TRIM72 / MG53 ELISA Kit - LS-F19896 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range To be determined

Rat TRIM72 / MG53 ELISA Kit - LS-F19894 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range To be determined

Human TRIM72 / MG53 ELISA Kit - LS-F19895 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range To be determined

Mouse TRIM72 / MG53 ELISA Kit (Sandwich ELISA) - LS-F13482 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 pg/ml Range 78-5000 pg/ml

Human TRIM72 ELISA Kit - E039520 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human TRIM72 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the m

TRIM72 ELISA Kit (Human) (OKEH05117) - OKEH05117 from Aviva Systems Biology Category ELISA Kit Prices $440.00 Sizes 96 wells Sensitivity 0.078 ng/mL Range 0.156-10 ng/mL

Human Tripartite motif-containing protein 72 ELISA Kit - EK4605 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Range 0.312-20 ng/ml

Tripartite motif-containing protein 72, ELISA Kit - MBS2882846 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tripartite motif-containing protein 72, ELISA Kit - MBS9428431 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Range 0.156-10 ng/mL

Tripartite motif-containing protein 72, ELISA Kit - MBS764404 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.9pg/ml Range 78-5000pg/ml

TRIM72 ELISA Kit (Human) (OKCA02318) - OKCA02318 from Aviva Systems Biology Category ELISA Kit Sensitivity 6.25 pg/mL Range 25 - 1,600 pg/mL

Mouse TRIM72 / MG53 ELISA Kit (Sandwich ELISA) - LS-F34262 from LifeSpan Bioscience Category ELISA Kit Sensitivity 46.9 Range 78-5000 pg/ml

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