TRIM72

Gene Symbol	TRIM72
Entrez Gene	493829
Alt Symbol	MG53
Species	Human
Gene Type	protein-coding
Description	tripartite motif containing 72, E3 ubiquitin protein ligase
Other Description	mitsugumin 53|mitsugumin-53|tripartite motif-containing 72|tripartite motif-containing protein 72
Swissprots	Q8NBD9 Q8N4X6 Q6ZMU5
Accessions	EAW52145 EAW52146 Q6ZMU5 AK090695 BAC03506 AK131485 BAD18630 BC033211 AAH33211 DA058421 DA821604 NM_001008274 NP_001008275
Function	Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane, sarcolemma {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}. Note=Tethered to plasma membrane and cytoplasmic vesicles via its interaction with phosphatidylserine. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TRIM72 full length protein - ab132761 from Abcam Category Protein Source Wheat germ Species Human

Human TRIM72 peptide - ab111656 from Abcam Category Peptide Species Human

Human TRIM72 protein fragment - ab112438 from Abcam Category Protein Source Wheat germ Species Human

TRIM72 / MG53 Antibody Blocking Peptide - LS-E1346 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRIM72 / MG53 Antibody Blocking Peptide - LS-E27511 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TRIM72 Protein - H00493829-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human TRIM72 Protein - H00493829-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TRIM72-Antibody-C-term-Blocking-peptide - BP11980b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Mammal TRIM72 protein - orb246934 from Biorbyt Category Protein Prices $502.00, $774.00, $1,054.00 Sizes 20 μg, 50 μg, 100 μg Species Human

TRIM72 Blocking Peptide - 33R-4890 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TRIM72 Blocking Peptide - 33R-1646 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TRIM72 Peptide - AC21-2334-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TRIM72 / MG53 - H00493829-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TRIM72 / MG53 - H00493829-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TRIM72 / MG53 - H00493829-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TRIM72 / MG53 - H00493829-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TRIM72 Peptide - 42-681P from ProSci Category Peptide Species Mouse, Rat

TRIM72 fusion protein - ag17756 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human TRIM72 - TRIM72-31611TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human Tripartite motif-containing protein 72(TRIM72) - CSB-YP744394HU CSB-BP744394HU CSB-EP744394HU from Cusabio Category Protein Source Yeast or Baculovirus or E.coli Species Human

Recombinant Tripartite motif-containing protein 72 - CSB-MP744394HU from Cusabio Category Protein Source Mammalian cell

TRIM72 / MG53 - TP318023 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

TRIM72, Peptide - MBS427580 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

Recombinant Human TRIM72 protein, MYC/DDK-tagged - TRIM72-12H from Creative Biomart Category Protein Source HEK293 Species Human

TRIM72 Recombinant Protein Antigen - NBP2-49157PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

Search more