TPX2

Gene Symbol	TPX2
Entrez Gene	22974
Alt Symbol	C20orf1, C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, REPP86, p100
Species	Human
Gene Type	protein-coding
Description	TPX2, microtubule-associated
Other Description	TPX2, microtubule-associated protein homolog|TPX2, microtubule-associated, homolog|differentially expressed in cancerous and non-cancerous lung cells 2|differentially expressed in lung cells|hepatocellular carcinoma-associated antigen 519|hepatocellular carcinoma-associated antigen 90|preferentially expressed in colorectal cancer|protein fls353|restricted expression proliferation associated protein 100|restricted expression proliferation-associated protein 100|targeting protein for Xklp2
Swissprots	Q9H1R4 Q9ULW0 Q9UL00 Q9NRA3 Q9Y2M1 Q9UFN9 Q96RR5
Accessions	EAW76418 EAW76419 EAW76420 EAW76421 EAW76422 Q9ULW0 AB024704 BAA76931 AB027467 BAA85893 AF098158 AAF03248 AF146731 AAD33965 AF244547 AAF81695 AF287265 AAK83033 AK001391 BAG50902 AK093379 AK312549 BAG35446 AL117534 CAB55982 AY734680 AAU29203 BC004136 AAH04136 BC011357 AAH11357 BC020207 AAH20207 BM835456 BU181208 CB960160 JF432351 ADZ15568 XM_011528697 XP_011526999 XM_011528698 XP_011527000 XM_011528699 XP_011527001 XM_011528700 XP_011527002 NM_012112 NP_036244
Function	Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. {ECO:0000269|PubMed:18663142, ECO:0000269|PubMed:19208764}.
Subcellular Location	Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules.
Tissue Specificity	Expressed in lung carcinoma cell lines but not in normal lung tissues.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TPX2 full length protein - ab119735 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human TPX2 protein fragment - ab153198 from Abcam Category Protein Source Wheat germ Species Human

TPX2 Antibody Blocking Peptide - LS-E3379 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TPX2 Antibody Blocking Peptide - LS-E6827 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TPX2 Antibody Blocking Peptide - LS-E16844 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TPX2 Protein - H00022974-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TPX2-Antibody-Center-Blocking-Peptide - BP14553c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

p100-Antibody-Blocking-Peptide - BP2044a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TPX2 Blocking Peptide - 33R-5427 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TPX2 / DIL2 - H00022974-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TPX2 / DIL2 - H00022974-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TPX2 fusion protein - ag0574 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

TPX2 fusion protein - Ag2334 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Recombinant Human TPX2, His-tagged - TPX2-7044H from Creative Biomart Category Protein Source Sf9 Cells Species Human

TPX2 protein-HIS Epitope - 009-001-U17 from Rockland Immunochemicals Inc Category Protein Prices $349.00 Sizes 50 µg Species Human

TPX2 protein-HIS Epitope - 009-001-U17S from Rockland Immunochemicals Inc Category Protein Prices $225.00 Sizes 20 µg Species Human

TPX2 (Q330) Peptide - BS3016P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Targeting protein for Xklp2(TPX2) - CSB-YP892151HU CSB-EP892151HU CSB-BP892151HU CSB-MP892151HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TPX2 / DIL2 - TP305821 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Targeting protein for Xklp2 (TPX2), Recombinant Protein - MBS1328348 from MyBioSource Category Protein Prices $1,560.00, $1,560.00, $1,790.00, $1,790.00, $2,685.00, $2,685.00, $3,125.00, $3,125.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

TPX2 Recombinant Protein Antigen - NBP1-88312PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TPX2 Peptide, Human - M34GP16506H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more