SWAP70

Gene Symbol SWAP70
Entrez Gene 23075
Alt Symbol HSPC321, SWAP-70
Species Human
Gene Type protein-coding
Description SWAP switching B-cell complex 70kDa subunit
Other Description switch-associated protein 70
Swissprots Q7LCY6 Q9P061 Q9P0Z8 D3DQV1 O75135 Q9UH65
Accessions EAW68582 EAW68583 EAW68584 EAW68585 Q9UH65 AB014540 BAA31615 AF134894 AAF61403 AF161439 AAF28999 AF210818 AAF24486 AI693686 AK027131 AK096859 BAG53381 AK304104 BAG65007 AL110154 BC000134 BC000616 AAH00616 DA413747 XM_005252830 XP_005252887 NM_001297714 NP_001284643 NM_015055 NP_055870
Function Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Cell membrane. Nucleus. Cell projection, lamellipodium. Note=In resting B-cells it is localized mainly in the cytoplasm and upon cell activation it is recruited to the plasma membrane and then translocates to the nucleus. In activated, class-switching B-cells it is associated with membrane IgG but not IgM. Localized to loose actin filament arrays located behind actively extending lamellipodia.
Tissue Specificity Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus- associated tissue (PubMed:10681448). Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages (PubMed:12925760). {ECO:0000269|PubMed:10681448, ECO:0000269|PubMed:12925760}.

SWAP70 (Human) IP-WB Antibody Pair - H00023075-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

SWAP70 (Human) Matched Antibody Pair - H00023075-AP51 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

Mouse SWAP70 ELISA Kit (Custom ELISA) - LS-F19878 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Bovine SWAP70 ELISA Kit (Custom ELISA) - LS-F19880 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Human SWAP70 ELISA Kit (Custom ELISA) - LS-F19881 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Chicken SWAP70 ELISA Kit (Custom ELISA) - LS-F19879 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Switch-associated protein 70, ELISA Kit - MBS288151 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Switch-associated protein 70, ELISA Kit - MBS288545 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.31 ng/ml -20.0 ng/ml.

Switch-associated protein 70, ELISA Kit - MBS288172 from MyBioSource

Category ELISA Kit
Prices $380.00, $500.00, $2,170.00, $3,840.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SWAP70 - EKH4546 from Nordic BioSite

Sensitivity 0.094ng/ml
Range 0.156-10ng/ml

SWAP70 ELISA Kit (Human) (OKEH01710) - OKEH01710 from Aviva Systems Biology

Category ELISA Kit
Prices $420.00
Sizes 96 wells
Sensitivity < 0.082 ng/mL
Range 0.156 - 10 ng/mL

Human SWAP70 ELISA Kit - E037064 from Biobool

Category ELISA Kit

Human Switch-associated protein 70 ELISA Kit - EK4594 from Signalway Antibody

Category ELISA Kit
Prices $599.00
Sizes 1x96t
Range 0.15 ng/mL -10.0 ng/mL

anti-SWAP70 antibody - ARG54106 from Arigo Biolaboratories

Category ELISA Kit

anti-SWAP70 antibody - ARG63197 from Arigo Biolaboratories

Category ELISA Kit

Switch-associated protein 70, ELISA Kit - MBS2883473 from MyBioSource

Category ELISA Kit
Prices $380.00, $500.00, $2,170.00, $3,840.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.156-10 ng/ml

Switch-associated protein 70, ELISA Kit - MBS9428420 from MyBioSource

Category ELISA Kit
Prices $555.00
Sizes 96 tests
Sensitivity Less than 0.082ng/mL
Range 0.156-10 ng/mL

Switch-associated protein 70, ELISA Kit - MBS764151 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094ng/ml
Range 0.156-10ng/ml

Human SWAP70 ELISA Kit (Sandwich ELISA) - LS-F35884 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 0.094
Range 0.156-10 ng/ml
Search more