PAK1IP1

Gene Symbol	PAK1IP1
Entrez Gene	55003
Alt Symbol	MAK11, PIP1, WDR84, bA421M1.5, hPIP1
Species	Human
Gene Type	protein-coding
Description	PAK1 interacting protein 1
Other Description	PAK/PLC-interacting protein 1|PAK1-interacting protein 1|WD repeat-containing protein 84|p21-activated protein kinase-interacting protein 1
Swissprots	Q96QJ8 Q96T87 Q5T4J2 Q9NWT1
Accessions	EAW55267 EAW55268 EAW55269 EAW55270 Q9NWT1 AF283303 AAK57477 AK000631 BAA91296 AK225516 BC010907 AAH10907 BU618231 DQ892798 ABM83724 DQ896045 ABM87044 XM_005249204 XP_005249261 XM_006715129 XP_006715192 XM_011514720 XP_011513022 XM_011514721 XP_011513023 NM_017906 NP_060376
Function	Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. {ECO:0000269|PubMed:11371639}.
Subcellular Location	Nucleus, nucleolus {ECO:0000269|PubMed:12429849}.
Tissue Specificity	Expressed in brain, colon, heart, kidney, liver, lung, muscle, peripheral blood leukocytes, placenta, small intestine, spleen and thymus. {ECO:0000269|PubMed:11371639}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PAK1 interacting protein 1 full length protein - ab162927 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human PAK1 interacting protein 1 Protein - H00055003-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

WDR84 / PIP1 - H00055003-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

PAK1IP1 fusion protein - Ag9016 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human PAK1IP1, GST-tagged - PAK1IP1-1514H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human p21-activated protein kinase-interacting protein 1(PAK1IP1) - CSB-YP873672HU CSB-EP873672HU CSB-BP873672HU CSB-MP873672HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

p21-activated protein kinase-interacting protein 1 (PAK1IP1), Recombinant Protein - MBS1281600 from MyBioSource Category Protein Prices $1,160.00, $1,160.00, $1,395.00, $1,395.00, $1,860.00, $1,860.00, $2,325.00, $2,325.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PAK1 interacting protein 1 Recombinant Protein Antigen - NBP1-90029PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PAK1IP1 Peptide, Human - M34GP11261H from Creative Peptides Category Peptide Source Synthetic. Species Human

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