PAK1IP1

Gene Symbol PAK1IP1
Entrez Gene 55003
Alt Symbol MAK11, PIP1, WDR84, bA421M1.5, hPIP1
Species Human
Gene Type protein-coding
Description PAK1 interacting protein 1
Other Description PAK/PLC-interacting protein 1|PAK1-interacting protein 1|WD repeat-containing protein 84|p21-activated protein kinase-interacting protein 1
Swissprots Q96QJ8 Q96T87 Q5T4J2 Q9NWT1
Accessions EAW55267 EAW55268 EAW55269 EAW55270 Q9NWT1 AF283303 AAK57477 AK000631 BAA91296 AK225516 BC010907 AAH10907 BU618231 DQ892798 ABM83724 DQ896045 ABM87044 XM_005249204 XP_005249261 XM_006715129 XP_006715192 XM_011514720 XP_011513022 XM_011514721 XP_011513023 NM_017906 NP_060376
Function Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. {ECO:0000269|PubMed:11371639}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:12429849}.
Tissue Specificity Expressed in brain, colon, heart, kidney, liver, lung, muscle, peripheral blood leukocytes, placenta, small intestine, spleen and thymus. {ECO:0000269|PubMed:11371639}.

PIP1 CRISPR/Cas9 KO Plasmid (h) - sc-407803 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PIP1 HDR Plasmid (h) - sc-407803-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PIP1 Double Nickase Plasmid (h) - sc-407803-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PIP1 Double Nickase Plasmid (h2) - sc-407803-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PIP1 CRISPR Activation Plasmid (h) - sc-407803-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PIP1 CRISPR Activation Plasmid (h2) - sc-407803-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PIP1 Lentiviral Activation Particles (h) - sc-407803-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PIP1 Lentiviral Activation Particles (h2) - sc-407803-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PIP1 siRNA (h) - sc-95403 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PIP1 shRNA Plasmid (h) - sc-95403-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PIP1 shRNA (h) Lentiviral Particles - sc-95403-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16286 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16286 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PAK1IP1 siRNA (Human) - CRJ0396 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PAK1IP1 (NM_017906.2) - SHH370148 from Creative biogene

Category siRNA
Species Reactivities Human

PAK1IP1 shRNA Plasmid (Human) - CHJ0396 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PAK1IP1 miRNA 3'UTR clone - MiUTR1H-07478 from Creative biogene

Species Reactivities Human
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