Gene Symbol | WFDC2 |
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Entrez Gene | 10406 |
Alt Symbol | EDDM4, HE4, WAP5, dJ461P17.6 |
Species | Human |
Gene Type | protein-coding |
Description | WAP four-disulfide core domain 2 |
Other Description | WAP domain containing protein HE4-V4|WAP four-disulfide core domain protein 2|epididymal protein 4|epididymal secretory protein E4|epididymis-specific, whey-acidic protein type, four-disulfide core|major epididymis-specific protein E4|putative protease inhibitor WAP5 |
Swissprots | Q96KJ1 Q8WXW2 Q6IB27 Q8WXV9 A2A2A5 A2A2A6 Q8WXW0 A6PVD5 Q14508 Q8WXW1 |
Accessions | CAV31701 CAV31702 CAY39341 EAW75836 EAW75837 EAW75838 EAW75839 EAW75840 Q14508 AF330259 AAL37485 AF330260 AAL37486 AF330261 AAL37487 AF330262 AAL37488 AK225528 AK290288 BAF82977 AK311966 AY212888 AAO52683 BC039816 BC046106 AAH46106 BI759775 CR456977 CAG33258 EU831749 ACE87267 EU831825 ACE86584 HQ448483 ADQ32963 X63187 CAA44869 XM_011528495 XP_011526797 NM_006103 NP_006094 NM_080733 NM_080734 NM_080735 NM_080736 |
Function | Broad range protease inhibitor. {ECO:0000269|PubMed:23139753}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:15781627, ECO:0000269|PubMed:23139753}. |
Tissue Specificity | Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. {ECO:0000269|PubMed:15781627}. |
HE4 peptide - ab181833 from Abcam
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Human HE4 full length protein - ab184603 from Abcam
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Human HE4 full length protein - ab132299 from Abcam
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Human HE4 full length protein - ab152016 from Abcam
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Human HE4 peptide - ab98946 from Abcam
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WFDC2 / HE4 Antibody Blocking Peptide - LS-E27337 from LifeSpan Bioscience
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WFDC2 / HE4 Antibody Blocking Peptide - LS-E27338 from LifeSpan Bioscience
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Recombinant Human HE4/WFDC2 Protein - H00010406-P01 from Novus Biologicals
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HE4 blocking peptide - GTX88122-PEP from GeneTex
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Mammal WFDC2 protein - orb246913 from Biorbyt
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Human WFDC2 His tag protein - orb84169 from Biorbyt
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HE4 protein - orb197711 from Biorbyt
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HE4 protein - orb197750 from Biorbyt
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HE4 protein - orb197732 from Biorbyt
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HE4 protein - orb197755 from Biorbyt
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Human WFDC2 protein - orb246156 from Biorbyt
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HE4 protein - orb197712 from Biorbyt
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canine WFDC2 protein - orb139879 from Biorbyt
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Human HE4 protein - orb49740 from Biorbyt
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WFDC2 protein - 30R-3146 from Fitzgerald
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Human HE4 Protein (Active) - abx060164 from Abbexa
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HE4 Peptide - AC21-2161-P from Abcore
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HE4 Peptide - AC21-2162-P from Abcore
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WFDC2 / WAP5 - H00010406-P01-10 from Acris Antibodies
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WFDC2 / WAP5 - H00010406-P01-25 from Acris Antibodies
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