PSMA7

Gene Symbol	PSMA7
Entrez Gene	5688
Alt Symbol	C6, HSPC, RC6-1, XAPC7
Species	Human
Gene Type	protein-coding
Description	proteasome (prosome, macropain) subunit, alpha type, 7
Other Description	proteasome subunit RC6-1|proteasome subunit XAPC7|proteasome subunit alpha 4|proteasome subunit alpha type-7
Swissprots	B2R515 Q9H4K5 O14818 Q5JXJ2 Q9UEU8 Q9BR53
Accessions	CBF59525 CBU84769 EAW75398 EAW75399 EAW75400 O14818 AF022815 AAB81515 AF054185 AAC99402 AK127210 AK312025 BAG34962 BC001895 BC004427 AAH04427 BC014999 AAH14999 BG575009 BI258951 BI906714 BT007165 AAP35829 BU632089 BU687782 DQ890589 ABM92206 DQ893754 ABM84680 HY039591 NM_002792 NP_002783 NM_152255
Function	The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen
Subcellular Location	Cytoplasm. Nucleus.
Top Pathways	Proteasome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

PSMA7-Over-expression-Lysate - LY10201a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

PSMA7 293T Cell Transient Overexpression Lysate(Denatured) - H00005688-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

PSMA7 overexpression lysate - LY400987 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PSMA7 293 Cell Lysate - 400926 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PSMA7 Overexpression Lysate (Native) - NBL1-14875 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PSMA7 Over-expression Lysate Product - GWB-D1B54F from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

PSMA7 Overexpression Lysate (Denatured) - H00005688-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human PSMA7 Knockdown Stable Cell Line - CSC-DC012582 from Creative biogene Category Cell Line Species Human

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