KCNJ3

Gene Symbol KCNJ3
Entrez Gene 3760
Alt Symbol GIRK1, KGA, KIR3.1
Species Human
Gene Type protein-coding
Description potassium channel, inwardly rectifying subfamily J, member 3
Other Description G protein-activated inward rectifier potassium channel 1|GIRK-1|inward rectifier K(+) channel Kir3.1|inward rectifier K+ channel KIR3.1|potassium channel, inwardly rectifying subfamily J member 3|potassium inwardly-rectifying channel subfamily J member 3 splice variant 1e|potassium inwardly-rectifying channel, subfamily J, member 3
Swissprots Q8TBI0 B4DEW7 P48549
Accessions AAX93197 EAX11461 P48549 AK026384 AK293824 BAG57228 AK293924 BAG57305 AW949825 BC022495 AAH22495 DQ892363 ABM83289 DQ895572 ABM86498 GU068048 ADB11083 GU074515 ADB11081 GU074516 ADB11082 U50964 AAB42176 NM_001260508 NP_001247437 NM_001260509 NP_001247438 NM_001260510 NP_001247439 NM_002239 NP_002230
Function This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
Subcellular Location Membrane; Multi-pass membrane protein.
Top Pathways Glutamatergic synapse, Dopaminergic synapse, Morphine addiction, Retrograde endocannabinoid signaling, Circadian entrainment

KIR3.1 (A-4) - sc-365457 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KIR3.1 (A-4): sc-365457. Western blot analysis of KIR3.1 expression in non-transfected: sc-117752 (A) and human KIR3.1 transfected: sc-159579 (B) 293T whole cell lysates.

KIR3.1 (G-15) - sc-16131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KIR3.1 (G-15): sc-16131. Immunofluorescence staining of methanol-fixed Sol8 cells showing membrane localization.

KIR3.1 (H-145) - sc-50410 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
KIR3.1 (H-145): sc-50410. Western blot analysis of KIR3.1 expression in mouse brain (A) and mouse cerebellum (B) tissue extracts.

KIR3.1 (S-15) - sc-22926 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KIR3.1 (S-15): sc-22926. Western blot analysis of KIR3.1 expression in non-transfected: sc-117752 (A) and human KIR3.1 transfected: sc-159579 (B) 293T whole cell lysates.

Anti-GIRK1 (phospho S185) antibody - ab61077 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of HeLa cells, using ab61077 at 1/500 dilution with or without phospho peptide.

Anti-GIRK1 antibody - ab61191 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of HeLa cells using ab61191 at 1/500 dilution. Samples were treated -/+ immunising peptide.

Anti-GIRK1 antibody - ab150488 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human heart tissue labelling GIRK1 with ab150488 antibody at a concentration of 15 µg/ml.

Anti-GIRK1 antibody - ab80970 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-GIRK1 antibody - ab96168 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GIRK1 antibody (ab96168) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLane 3 : HeLa whole cell lysateLysates/proteins at 30 µg per lane.

Anti-GIRK1 antibody - ab66503 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GIRK1 antibody [3E11] - ab119246 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E11
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using ab119246 at 1/150.

Anti-GIRK1 antibody [EPR6363] - ab129182 from Abcam

Prices $394.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6363
All lanes : Anti-GIRK1 antibody [EPR6363] (ab129182) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : Fetal heart cell lysateLane 3 : NIH/3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-rabbit HRP

Anti-KCNJ3 antibody - ab116126 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KCNJ3 antibody (ab116126) at 1 µg/ml + Mouse kidney lysate at 10 µg

Anti-KCNJ3 / GIRK1 Antibody (clone 1G3) - LS-C173691 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1G3
IHC of paraffin-embedded Human endometrium tissue using anti-KCNJ3 mouse monoclonal antibody.

Anti-KCNJ3 / GIRK1 Antibody (Cytoplasmic Domain) - LS-C94239 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNJ3 / GIRK1 Antibody (C-Terminus) - LS-C153450 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNJ3 / GIRK1 Antibody (C-Terminus) - LS-C144783 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ3 / GIRK1 Antibody (aa361-410) - LS-C145543 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KCNJ3 / Kir3.1 antibody LS-C145543 Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.

Anti-KCNJ3 / GIRK1 Antibody (aa390-418) - LS-C165433 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
KCNJ3 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The KCNJ3 antibody detected the KCNJ3 protein (arrow).

Anti-KCNJ3 / GIRK1 Antibody (aa390-418) - LS-C165432 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
KCNJ3 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The KCNJ3 antibody detected the KCNJ3 protein (arrow).

Anti-KCNJ3 / GIRK1 Antibody (Extracellular Domain, clone EPR6363) - LS-C152465 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6363
Western blot analysis on (A) HeLa, (B) fetal heart, and (C) NIH/3T3 lysates using anti-GIRK1 antibody.

Anti-KCNJ3 / GIRK1 Antibody (Phe181) - LS-C176518 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of KIR3.1 (F181) pAb in extracts from NIH/3T3 cells.

Anti-KCNJ3 / GIRK1 Antibody (aa151-200) - LS-C117945 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HeLa cells, using GIRK1/KIR3.1/KCNJ3 (Ab-185) Antibody. The picture on the right is treated with the synthesized peptide.

Anti-KCNJ3 / GIRK1 Antibody (clone 2F2) - LS-C173660 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KCNJ3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-KCNJ3.

Anti-KCNJ3 / GIRK1 Antibody (aa248-501) - LS-C186022 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded DU145 xenograft using GIRK1 antibody at 1:100 dilution.
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