KCNJ3

Gene Symbol	KCNJ3
Entrez Gene	3760
Alt Symbol	GIRK1, KGA, KIR3.1
Species	Human
Gene Type	protein-coding
Description	potassium channel, inwardly rectifying subfamily J, member 3
Other Description	G protein-activated inward rectifier potassium channel 1|GIRK-1|inward rectifier K(+) channel Kir3.1|inward rectifier K+ channel KIR3.1|potassium channel, inwardly rectifying subfamily J member 3|potassium inwardly-rectifying channel subfamily J member 3 splice variant 1e|potassium inwardly-rectifying channel, subfamily J, member 3
Swissprots	Q8TBI0 B4DEW7 P48549
Accessions	AAX93197 EAX11461 P48549 AK026384 AK293824 BAG57228 AK293924 BAG57305 AW949825 BC022495 AAH22495 DQ892363 ABM83289 DQ895572 ABM86498 GU068048 ADB11083 GU074515 ADB11081 GU074516 ADB11082 U50964 AAB42176 NM_001260508 NP_001247437 NM_001260509 NP_001247438 NM_001260510 NP_001247439 NM_002239 NP_002230
Function	This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
Subcellular Location	Membrane; Multi-pass membrane protein.
Top Pathways	Glutamatergic synapse, Dopaminergic synapse, Morphine addiction, Retrograde endocannabinoid signaling, Circadian entrainment

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KCNJ3 / GIRK1 Antibody Blocking Peptide - LS-E12486 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNJ3 / GIRK1 Antibody Blocking Peptide - LS-E29689 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KCNJ3-Antibody-C-term-Blocking-Peptide - BP14225b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KCNJ3 fusion protein - ag10581 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

KCNJ3 fusion protein - Ag10844 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

KIR3.1 (F181) Peptide - BS1648P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Kir3.1 Recombinant Protein Antigen - NBP1-89770PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Kir3.1 (pS185) Blocking Peptide - abx161910 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Monkey

Kir3.1 Blocking Peptide - abx161911 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken

KCNJ3 Peptide, Human - M34GP07969H from Creative Peptides Category Peptide Source Synthetic. Species Human

Kir3.1 (pS185) Blocking Peptide - CBP4699 from Cohesion Biosciences Category Peptide Prices $150.00, $450.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken, Monkey

Kir3.1 Blocking Peptide - CBP4700 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken

G protein-activated inward rectifier potassium channel 1 (KCNJ3), Recombinant Protein - MBS964670 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

G protein-activated inward rectifier potassium channel 1 (KCNJ3), Recombinant Protein - MBS7017700 from MyBioSource Category Protein Prices $1,300.00, $2,285.00, $3,495.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Kir3.1 (Phospho-S185) peptide - orb315843 from Biorbyt Category Peptide

Kir3.1 peptide - orb315844 from Biorbyt Category Peptide

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