LMCD1

Gene Symbol LMCD1
Entrez Gene 29995
Alt Symbol -
Species Human
Gene Type protein-coding
Description LIM and cysteine-rich domains 1
Other Description LIM and cysteine-rich domains protein 1|dyxin
Swissprots B4DG80 Q9NZU5
Accessions EAW63937 EAW63938 Q9NZU5 AF169284 AAF34411 AF216709 AAG36778 AI693011 AI951010 AK022176 BAB13976 AK074448 AK293849 BAG57247 AK294455 BAG57691 AK300803 BAH13351 BC000646 AAH00646 BU619403 BX114807 CN388104 DQ891747 ABM82673 DQ894926 ABM85852 N95437 W47274 XM_011533649 XP_011531951 NM_001278233 NP_001265162 NM_001278234 NP_001265163 NM_001278235 NP_001265164 NM_014583 NP_055398
Function Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway. {ECO:0000250, ECO:0000269|PubMed:20026769}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=May shuttle between the cytoplasm and the nucleus. {ECO:0000250}.
Tissue Specificity Expressed in the heart (at protein level). Expressed in many tissues with highest abundance in skeletal muscle. {ECO:0000269|PubMed:20026769}.

LMCD1 CRISPR/Cas9 KO Plasmid (h) - sc-412065 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LMCD1 HDR Plasmid (h) - sc-412065-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LMCD1 Double Nickase Plasmid (h) - sc-412065-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LMCD1 Double Nickase Plasmid (h2) - sc-412065-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LMCD1 CRISPR Activation Plasmid (h) - sc-412065-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LMCD1 CRISPR Activation Plasmid (h2) - sc-412065-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LMCD1 Lentiviral Activation Particles (h) - sc-412065-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LMCD1 Lentiviral Activation Particles (h2) - sc-412065-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LMCD1 siRNA (h) - sc-78291 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LMCD1 shRNA Plasmid (h) - sc-78291-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LMCD1 shRNA (h) Lentiviral Particles - sc-78291-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU155951 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11767 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11767 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04685 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04685

LMCD1 siRNA (Human) - CRH9324 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LMCD1 RNAi - H00029995-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human LMCD1 (NM_014583.2) - SHH330955 from Creative biogene

Category siRNA
Species Reactivities Human

LMCD1 shRNA Plasmid (Human) - CHH9324 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LMCD1 miRNA 3'UTR clone - MiUTR1H-05713 from Creative biogene

Species Reactivities Human
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