SMARCA5

Gene Symbol	SMARCA5
Entrez Gene	8467
Alt Symbol	ISWI, SNF2H, WCRF135, hISWI, hSNF2H
Species	Human
Gene Type	protein-coding
Description	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Other Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5|sucrose nonfermenting protein 2 homolog|sucrose nonfermenting-like 5
Swissprots	O60264
Accessions	AAY40920 AAY40965 EAX05071 O60264 AB010882 BAA25173 AF086544 AK123439 AK302841 BAG64032 AK308424 AK316444 BAH14815 AL157495 AU132439 BC023144 AAH23144 JF432501 ADZ15718 XM_011532361 XP_011530663 NM_003601 NP_003592
Function	Helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity. Complexes containing SMARCA5 are capable of forming ordered nucleosome arrays on chromatin; this may require intact histone H4 tails. Also required for replication of pericentric heterochromatin in S-phase specifically in conjunction with BAZ1A. Probably plays a role in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1 corepressor complex to the rDNA promoter. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. Essential component of the NoRC (nucleolar r
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00624, ECO:0000269|PubMed:12434153}.
Tissue Specificity	Ubiquitously expressed.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SNF2H peptide - ab5160 from Abcam Category Peptide

Human SNF2H protein fragment - ab152876 from Abcam Category Protein Source Wheat germ Species Human

SMARCA5 / SNF2H Antibody Blocking Peptide - LS-E1090 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMARCA5 / SNF2H Antibody Blocking Peptide - LS-E3460 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMARCA5 / SNF2H Antibody Blocking Peptide - LS-E25149 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMARCA5 / SNF2H Antibody Blocking Peptide - LS-E10455 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMARCA5/SNF2H Partial Recombinant Protein - H00008467-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ISWI-Antibody-C-term-Blocking-peptide - BP11583b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ISWI-Antibody-N-term-Blocking-Peptide - BP14644a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SMARCA5 - H00008467-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SMARCA5 - H00008467-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SMARCA5 fusion protein - Ag3759 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SMARCA5, GST-tagged - SMARCA5-2805H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human SWI/SNF-related matrix-associated actin-dependent regulator of - CSB-YP021802HU CSB-EP021802HU CSB-BP021802HU CSB-MP021802HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SMARCA5 - TP303775 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SMARCA5/SNF2H Recombinant Protein Antigen - NBP1-89692PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SNF2h antibody ( mAb ) , 200 ul - HM-AB1995 from Novatein Biosciences Prices $442.00 Sizes 200 µl

SNF2h antibody ( mAb ) , 10 ul - HM-AB1996 from Novatein Biosciences Prices $91.00 Sizes 10 µl

SMARCA5 Peptide, Human - M34GP14725H from Creative Peptides Category Peptide Source Synthetic. Species Human

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5), partial, Recombinant Protein - MBS1184717 from MyBioSource Category Protein Prices $1,695.00, $1,850.00, $1,995.00, $2,110.00, $2,310.00, $2,345.00, $2,635.00, $2,905.00, $3,340.00, $4,170.00 Sizes 50 µg (Baculovirus), 500 µg (E-Coli), 500 µg (Yeast), 100 µg (Baculovirus), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 1 mg (Yeast), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more