ATG4B

Gene Symbol ATG4B
Entrez Gene 23192
Alt Symbol APG4B, AUTL1
Species Human
Gene Type protein-coding
Description autophagy related 4B, cysteine peptidase
Other Description APG4 autophagy 4 homolog B|ATG4 autophagy related 4 homolog B|AUT-like 1 cysteine endopeptidase|autophagin-1|autophagy-related cysteine endopeptidase 1|autophagy-related protein 4 homolog B|cysteine protease ATG4B|hAPG4B
Swissprots Q6ZUV8 Q53NU4 Q96SZ1 Q96K96 Q9Y2F2 Q96K07 Q8WYM9 Q9Y4P1 B7WNK2
Accessions AAY14919 EAW71278 EAW71279 EAW71280 EAW71281 Q9Y4P1 AB023160 BAA76787 AB066215 BAB83890 AJ504652 CAD43219 AK027332 BAB55042 AK027462 BAB55127 AK027763 BAB55353 AK123425 BAG53904 AK125277 BAC86110 AK296818 BAG59391 AK298109 BAG60394 AK302963 BAG64112 AK316167 BAH14538 AL050288 AL080168 CAB45756 AL133638 AM393751 CAL38626 BC000719 AAH00719 BX648007 CAH56198 DQ891869 ABM82795 XM_005246992 XP_005247049 XM_005246993 XP_005247050 XM_005246995 XP_005247052 XM_005246996 XP_005247053 XM_011510836 XP_011509138 XM_011510837 XP_011509139 XM_011510838 XP_011509140 XM_011510839 XP_011509141 NM_013325 NP_037457 NM_178326 NP_847896
Function Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. {ECO:0000269|PubMed:15169837, ECO:0000269|PubMed:15187094, ECO:0000269|PubMed:17347651, ECO:0000269|PubMed:19322194, ECO:0000269|PubMed:21177865, ECO:0000269|PubMed:22302004}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas. {ECO:0000269|PubMed:12446702, ECO:0000269|PubMed:15169837}.
Top Pathways Regulation of autophagy

Cysteine protease ATG4B (ATG4B), Human, ELISA Kit - E01C1204 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7224081 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7228694 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7227939 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7226180 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/mL.

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7209286 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/mL.

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7206733 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7222119 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7217522 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7230584 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7219656 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7251183 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cysteine protease ATG4B (ATG4B), ELISA Kit - MBS7218943 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human ATG4B ELISA Kit - E010806 from Biobool

Category ELISA Kit

anti-ATG4B antibody - ARG54818 from Arigo Biolaboratories

Category ELISA Kit
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