Gene Symbol | NUDT7 |
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Entrez Gene | 283927 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
Other Description | peroxisomal coenzyme A diphosphatase NUDT7 |
Swissprots | B4DLE5 H3BUB8 P0C024 |
Accessions | EAW95595 EAW95596 P0C024 AA227330 AA579048 AI927964 AK296963 BAG59507 BC172303 AAI72303 BU579534 BX387030 BX494638 CN297379 ES309123 EU981826 ACH71652 XM_011523032 XP_011521334 XM_011523033 XP_011521335 NM_001105663 NP_001099133 NM_001243657 NP_001230586 NM_001243660 NP_001230589 NM_001243661 NP_001230590 |
Function | Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into 3',5'-ADP and 4'- phosphopantetheine. Has no activity toward NDP-sugars, CDP- alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity). {ECO:0000250}. |
Subcellular Location | Peroxisome {ECO:0000250}. |
Tissue Specificity | Expressed in liver, kidney, pancreas, pituitary, small intestine, spleen, heart and placenta. Weakly expressed in brain. {ECO:0000269|PubMed:11415433}. |
Top Pathways | Peroxisome |
NUDT7 (E-9) - sc-390911 from Santa Cruz Biotechnology
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NUDT7 (F-20) - sc-243640 from Santa Cruz Biotechnology
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NUDT7 (N-15) - sc-243638 from Santa Cruz Biotechnology
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Anti-NUDT7 antibody - ab133800 from Abcam
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Anti-NUDT7 Antibody (aa59-108) - LS-C152131 from LifeSpan Bioscience
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Anti-NUDT7 Antibody - LS-C137239 from LifeSpan Bioscience
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NUDT7 Antibody - NBP1-91125 from Novus Biologicals
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Anti-NUDT7 antibody produced in rabbit - HPA042042 from Sigma-Aldrich
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NUDT7 Antibody - N-terminal region (ARP66063_P050) - ARP66063_P050 from Aviva Systems Biology
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NUDT7 antibody - orb76882 from Biorbyt
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NUDT7 Antibody - abx038160 from Abbexa
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NUDT7 Antibody - 39404 from Signalway Antibody
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NUDT7 Antibody - E300129 from Enogene
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Anti-NUDT7 (aa 59-108) polyclonal antibody - DPABH-25383 from Creative Diagnostics
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NUDT7, Polyclonal Antibody - MBS416528 from MyBioSource
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NUDT7, Polyclonal Antibody - MBS852072 from MyBioSource
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NUDT7-Antibody-N-terminal-region-AI15302 - AI15302 from Abgent, a WuXi AppTec company
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NUDT7, Polyclonal Antibody - MBS9401046 from MyBioSource
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NUDT7 (D-1) - sc-515481 from Santa Cruz Biotechnology
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NUDT7 antibody - TA338314 from Acris Antibodies
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NUDT7 antibody - orb309301 from Biorbyt
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NUDT7 antibody (FITC) - orb318564 from Biorbyt
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Anti-NUDT7 Antibody A10663 - A10663 from Boster Bio
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NUDT7 Antibody - N-terminal region : Biotin (ARP66063_P050-Biotin) - ARP66063_P050-Biotin from Aviva Systems Biology
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NUDT7 Antibody - N-terminal region : FITC (ARP66063_P050-FITC) - ARP66063_P050-FITC from Aviva Systems Biology
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