NUDT7

Gene Symbol NUDT7
Entrez Gene 283927
Alt Symbol -
Species Human
Gene Type protein-coding
Description nudix (nucleoside diphosphate linked moiety X)-type motif 7
Other Description peroxisomal coenzyme A diphosphatase NUDT7
Swissprots B4DLE5 H3BUB8 P0C024
Accessions EAW95595 EAW95596 P0C024 AA227330 AA579048 AI927964 AK296963 BAG59507 BC172303 AAI72303 BU579534 BX387030 BX494638 CN297379 ES309123 EU981826 ACH71652 XM_011523032 XP_011521334 XM_011523033 XP_011521335 NM_001105663 NP_001099133 NM_001243657 NP_001230586 NM_001243660 NP_001230589 NM_001243661 NP_001230590
Function Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into 3',5'-ADP and 4'- phosphopantetheine. Has no activity toward NDP-sugars, CDP- alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity). {ECO:0000250}.
Subcellular Location Peroxisome {ECO:0000250}.
Tissue Specificity Expressed in liver, kidney, pancreas, pituitary, small intestine, spleen, heart and placenta. Weakly expressed in brain. {ECO:0000269|PubMed:11415433}.
Top Pathways Peroxisome

NUDT7 CRISPR/Cas9 KO Plasmid (h) - sc-418706 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT7 HDR Plasmid (h) - sc-418706-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT7 Double Nickase Plasmid (h) - sc-418706-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT7 Double Nickase Plasmid (h2) - sc-418706-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT7 CRISPR Activation Plasmid (h) - sc-418706-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT7 CRISPR Activation Plasmid (h2) - sc-418706-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT7 Lentiviral Activation Particles (h) - sc-418706-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NUDT7 Lentiviral Activation Particles (h2) - sc-418706-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MISSION® esiRNA - EHU149151 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15607 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15607 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NUDT7 siRNA (Human) - CRJ6945 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Nudt7 (NM_001105663.2) - SHH356232 from Creative biogene

Category siRNA
Species Reactivities Human

Human NUDT7 siRNA - orb277446 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NUDT7 shRNA Plasmid (Human) - CHJ6945 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NUDT7 miRNA 3'UTR clone - MiUTR3H-10496 from Creative biogene

Species Reactivities Human
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