Gene Symbol | NUDT7 |
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Entrez Gene | 283927 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
Other Description | peroxisomal coenzyme A diphosphatase NUDT7 |
Swissprots | B4DLE5 H3BUB8 P0C024 |
Accessions | EAW95595 EAW95596 P0C024 AA227330 AA579048 AI927964 AK296963 BAG59507 BC172303 AAI72303 BU579534 BX387030 BX494638 CN297379 ES309123 EU981826 ACH71652 XM_011523032 XP_011521334 XM_011523033 XP_011521335 NM_001105663 NP_001099133 NM_001243657 NP_001230586 NM_001243660 NP_001230589 NM_001243661 NP_001230590 |
Function | Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into 3',5'-ADP and 4'- phosphopantetheine. Has no activity toward NDP-sugars, CDP- alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity). {ECO:0000250}. |
Subcellular Location | Peroxisome {ECO:0000250}. |
Tissue Specificity | Expressed in liver, kidney, pancreas, pituitary, small intestine, spleen, heart and placenta. Weakly expressed in brain. {ECO:0000269|PubMed:11415433}. |
Top Pathways | Peroxisome |
NUDT7 Antibody Blocking Peptide - LS-E24024 from LifeSpan Bioscience
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NUDT7-Antibody-Center-Blocking-Peptide - BP9149c from Abgent, a WuXi AppTec company
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Recombinant Human NUDT7 - NUDT7-925H from Creative Biomart
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Recombinant Human Peroxisomal coenzyme A diphosphatase NUDT7(NUDT7) - CSB-YP016177HU CSB-EP016177HU CSB-BP016177HU CSB-MP016177HU from Cusabio
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NUDT7 (transcript variant 1) - TP325300 from Acris Antibodies
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Peroxisomal coenzyme A diphosphatase NUDT7 (NUDT7), Recombinant Protein - MBS964627 from MyBioSource
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NUDT7 Recombinant Protein Antigen - NBP1-91125PEP from Novus Biologicals
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NUDT7 Peptide, Human - M34GP10720H from Creative Peptides
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