Gene Symbol | PHLDA1 |
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Entrez Gene | 22822 |
Alt Symbol | DT1P1B11, PHRIP, TDAG51 |
Species | Human |
Gene Type | protein-coding |
Description | pleckstrin homology-like domain, family A, member 1 |
Other Description | PQ-rich protein|PQR protein|T-cell death-associated gene 51 protein|apoptosis-associated nuclear protein|pleckstrin homology-like domain family A member 1|proline- and glutamine-rich protein|proline- and histidine-rich protein|proline-histidine rich protein |
Swissprots | Q8WV24 Q2TAN2 Q15184 A1A4G9 Q9NZ17 |
Accessions | AAF64165 EAW97312 EAW97313 Q8WV24 AF220656 AAF36387 AK026181 AK304224 BAG65096 BC017756 BC018929 AAH18929 BC037430 BC039558 BC047362 BC065825 BC110820 AAI10821 BC126425 AAI26426 BC130427 AAI30428 DR002699 JF432667 ADZ15884 U92983 Z50194 CAA90576 NM_007350 NP_031376 |
Function | Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation. {ECO:0000269|PubMed:11369516, ECO:0000269|PubMed:12738777}. |
Subcellular Location | Cytoplasm. Cytoplasmic vesicle membrane. Nucleus, nucleolus. Note=Colocalizes with intracellular vesicles. |
Tissue Specificity | Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level). {ECO:0000269|PubMed:12384558, ECO:0000269|PubMed:12738777}. |
Human PHLDA1 full length protein - ab153187 from Abcam
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Human PHLDA1 protein fragment - ab153188 from Abcam
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PHLDA1 Antibody Blocking Peptide - LS-E6211 from LifeSpan Bioscience
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PHLDA1 Antibody Blocking Peptide - LS-E19760 from LifeSpan Bioscience
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PHLDA1 Antibody Blocking Peptide - LS-E19761 from LifeSpan Bioscience
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Recombinant Human PHLDA1 Protein - H00022822-Q01 from Novus Biologicals
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PHLDA1 Recombinant Protein - H00022822-P01 from Novus Biologicals
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PHLDA1-Antibody-N-term-Blocking-Peptide - BP18855a from Abgent, a WuXi AppTec company
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PHLDA1 Blocking Peptide - 33R-6986 from Fitzgerald
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PHLDA1 Blocking Peptide - 33R-4806 from Fitzgerald
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TDAG51 / PHLDA1 - H00022822-P01-10 from Acris Antibodies
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TDAG51 / PHLDA1 - H00022822-P01-25 from Acris Antibodies
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TDAG51 / PHLDA1 - H00022822-Q01-10 from Acris Antibodies
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TDAG51 / PHLDA1 - H00022822-Q01-25 from Acris Antibodies
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PHLDA1 fusion protein - Ag13125 from Proteintech Group
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PHLDA1 fusion protein - ag13064 from Proteintech Group
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Recombinant Human PHLDA1, GST-tagged - PHLDA1-1687H from Creative Biomart
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TDAG51 (A149) Peptide - BS2579P from Bioworld Technology
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Recombinant Human Pleckstrin homology-like domain family A member 1(PHLDA1) - CSB-YP845148HU CSB-EP845148HU CSB-BP845148HU CSB-MP845148HU from Cusabio
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Pleckstrin homology-like domain family A member 1 (PHLDA1), Recombinant Protein - MBS1401532 from MyBioSource
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PHLDA1 Recombinant Protein Antigen - NBP1-84969PEP from Novus Biologicals
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PHLDA1 Peptide, Human - M34GP11713H from Creative Peptides
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PHLDA1 Recombinant Protein Antigen - NBP2-56404PEP from Novus Biologicals
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Recombinant Human Pleckstrin homology-like domain family A member 1 (PHLDA1) - RPC23415 from Biomatik
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