Gene Symbol | PHLDA1 |
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Entrez Gene | 22822 |
Alt Symbol | DT1P1B11, PHRIP, TDAG51 |
Species | Human |
Gene Type | protein-coding |
Description | pleckstrin homology-like domain, family A, member 1 |
Other Description | PQ-rich protein|PQR protein|T-cell death-associated gene 51 protein|apoptosis-associated nuclear protein|pleckstrin homology-like domain family A member 1|proline- and glutamine-rich protein|proline- and histidine-rich protein|proline-histidine rich protein |
Swissprots | Q8WV24 Q2TAN2 Q15184 A1A4G9 Q9NZ17 |
Accessions | AAF64165 EAW97312 EAW97313 Q8WV24 AF220656 AAF36387 AK026181 AK304224 BAG65096 BC017756 BC018929 AAH18929 BC037430 BC039558 BC047362 BC065825 BC110820 AAI10821 BC126425 AAI26426 BC130427 AAI30428 DR002699 JF432667 ADZ15884 U92983 Z50194 CAA90576 NM_007350 NP_031376 |
Function | Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation. {ECO:0000269|PubMed:11369516, ECO:0000269|PubMed:12738777}. |
Subcellular Location | Cytoplasm. Cytoplasmic vesicle membrane. Nucleus, nucleolus. Note=Colocalizes with intracellular vesicles. |
Tissue Specificity | Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level). {ECO:0000269|PubMed:12384558, ECO:0000269|PubMed:12738777}. |
TDAG51 (M-20) - sc-6142 from Santa Cruz Biotechnology
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TDAG51 (L-19) - sc-6143 from Santa Cruz Biotechnology
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TDAG51 (H-150) - sc-28242 from Santa Cruz Biotechnology
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TDAG51 (RN-6E2) - sc-23866 from Santa Cruz Biotechnology
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Anti-PHLDA1 antibody - ab67849 from Abcam
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Anti-PHLDA1 antibody [EPR6674] - ab133654 from Abcam
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Anti-PHLDA1 antibody - N-terminal - ab138640 from Abcam
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Anti-PHLDA1 Antibody (aa23-49, Azide-free, HRP) - LS-C266192 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa271-320) - LS-C119586 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa218-267) - LS-C81939 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa290-339) - LS-C81940 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa23-49) - LS-C158590 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa23-49, PE) - LS-C266193 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa23-49, AP) - LS-C284558 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa23-49, APC) - LS-C284559 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa23-49, Biotin) - LS-C284560 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa22-49) - LS-C323995 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa100-149) - LS-C200487 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody - LS-C332531 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (Internal, clone EPR6674) IHC-plus™ - LS-B9092 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody - LS-C190153 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (aa23-49, FITC) - LS-C266191 from LifeSpan Bioscience
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Anti-PHLDA1 Antibody (Ala149) - LS-C177073 from LifeSpan Bioscience
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PHLDA1 Antibody - NBP1-84969 from Novus Biologicals
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PHLDA1 Antibody - NBP1-53066 from Novus Biologicals
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