PHLDA1

Gene Symbol PHLDA1
Entrez Gene 22822
Alt Symbol DT1P1B11, PHRIP, TDAG51
Species Human
Gene Type protein-coding
Description pleckstrin homology-like domain, family A, member 1
Other Description PQ-rich protein|PQR protein|T-cell death-associated gene 51 protein|apoptosis-associated nuclear protein|pleckstrin homology-like domain family A member 1|proline- and glutamine-rich protein|proline- and histidine-rich protein|proline-histidine rich protein
Swissprots Q8WV24 Q2TAN2 Q15184 A1A4G9 Q9NZ17
Accessions AAF64165 EAW97312 EAW97313 Q8WV24 AF220656 AAF36387 AK026181 AK304224 BAG65096 BC017756 BC018929 AAH18929 BC037430 BC039558 BC047362 BC065825 BC110820 AAI10821 BC126425 AAI26426 BC130427 AAI30428 DR002699 JF432667 ADZ15884 U92983 Z50194 CAA90576 NM_007350 NP_031376
Function Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation. {ECO:0000269|PubMed:11369516, ECO:0000269|PubMed:12738777}.
Subcellular Location Cytoplasm. Cytoplasmic vesicle membrane. Nucleus, nucleolus. Note=Colocalizes with intracellular vesicles.
Tissue Specificity Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level). {ECO:0000269|PubMed:12384558, ECO:0000269|PubMed:12738777}.

TDAG51 (M-20) - sc-6142 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TDAG51 (M-20): sc-6142. Immunofluorescence staining of methanol-fixed Hep G2 cells showing cytoplasmic localization.

TDAG51 (L-19) - sc-6143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TDAG51 (L-19): sc-6143. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human pancreas tissue (A) and immunofluorescence staining of methanol-fixed Hep G2 cells (B) showing cytoplasmic localization.

TDAG51 (H-150) - sc-28242 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TDAG51 (H-150): sc-28242. Western blot analysis of TDAG51 expression in Hep G2 whole cell lysate.

TDAG51 (RN-6E2) - sc-23866 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TDAG51 (RN-6E2): sc-23866. Western blot analysis of TDAG51 expression in Hep G2 (A), HUVEC (B) and HeLa (C) whole cell lysates.

Anti-PHLDA1 antibody - ab67849 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PHLDA1 antibody (ab67849) at 1/500 dilutionLane 1 : PHLDA1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-PHLDA1 antibody [EPR6674] - ab133654 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6674
All lanes : Anti-PHLDA1 antibody [EPR6674] (ab133654) at 1/10000 dilutionLane 1 : Human melanoma tissue lysateLane 2 : A375 cell lysateLane 3 : BxPC3 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-PHLDA1 antibody - N-terminal - ab138640 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PHLDA1 antibody - N-terminal (ab138640) at 1/100 dilution + A2058 cell lysate at 35 µg

Anti-PHLDA1 Antibody (aa23-49, Azide-free, HRP) - LS-C266192 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHLDA1 Antibody (aa271-320) - LS-C119586 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from RAW264.7 cells, using PHLA1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-PHLDA1 Antibody (aa218-267) - LS-C81939 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PHLDA1 Antibody (aa290-339) - LS-C81940 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PHLDA1 Antibody (aa23-49) - LS-C158590 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PHLDA1 Antibody western blot of A2058 cell line lysates (35 ug/lane). The PHLDA1 antibody detected the PHLDA1 protein (arrow).

Anti-PHLDA1 Antibody (aa23-49, PE) - LS-C266193 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHLDA1 Antibody (aa23-49, AP) - LS-C284558 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHLDA1 Antibody (aa23-49, APC) - LS-C284559 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHLDA1 Antibody (aa23-49, Biotin) - LS-C284560 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHLDA1 Antibody (aa22-49) - LS-C323995 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHLDA1 Antibody (aa100-149) - LS-C200487 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from K562 cells using PHLA1 antibody.

Anti-PHLDA1 Antibody - LS-C332531 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using PHLDA1 antibody.

Anti-PHLDA1 Antibody (Internal, clone EPR6674) IHC-plus™ - LS-B9092 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6674
Anti-PHLDA1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PHLDA1 Antibody - LS-C190153 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PHLDA1 Antibody (aa23-49, FITC) - LS-C266191 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHLDA1 Antibody (Ala149) - LS-C177073 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of TDAG51 (A149) pAb in extracts from RAW264.7.

PHLDA1 Antibody - NBP1-84969 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: PHLDA1 Antibody [NBP1-84969] - Staining of human salivary gland shows strong positivity in glandular cells.

PHLDA1 Antibody - NBP1-53066 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PHLDA1 Antibody [NBP1-53066] - Human Placenta lysate, concentration 0.2-1 ug/ml.
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