Gene Symbol | SSPN |
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Entrez Gene | 8082 |
Alt Symbol | DAGA5, KRAG, NSPN, SPN1, SPN2 |
Species | Human |
Gene Type | protein-coding |
Description | sarcospan |
Other Description | K-ras oncogene-associated protein|Kras oncogene-associated|kirsten-ras-associated protein|microspan|nanospan|sarcospan (Kras oncogene-associated gene) |
Swissprots | Q14714 B3KS67 |
Accessions | EAW96532 Q14714 AF016028 AAC61660 AK092925 BAG52629 AK304667 BAG65442 AK314353 BAG36988 AL136756 CAB66690 AM392675 CAL37553 AM392714 CAL37592 BC041929 BC062299 AAH62299 BP341300 CA419006 DA073350 DQ897666 ABI78937 EU433933 ACA09756 X89105 CAA61479 XM_011520853 XP_011519155 XM_011520854 XP_011519156 XM_011520855 XP_011519157 NM_001135823 NP_001129295 NM_005086 NP_005077 |
Function | Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane, sarcolemma {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Also found in myotendinous junctions and in the postsynaptic membrane of neuromuscular junctions. {ECO:0000250}. |
Tissue Specificity | Isoform 1 is expressed exclusively in heart and skeletal muscle. Isoform 2 is expressed in heart, skeletal muscle, thymus, prostate, testis, ovary, small intestine, colon and spleen. |
Human SSPN full length protein - ab159942 from Abcam
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SSPN / Sarcospan Antibody Blocking Peptide - LS-E16956 from LifeSpan Bioscience
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Recombinant Human SSPN Protein - H00008082-P01 from Novus Biologicals
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Sarcospan Blocking Peptide - 33R-1245 from Fitzgerald
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SNUPN protein (His tag) - 80R-1402 from Fitzgerald
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Sarcospan / SSPN - H00008082-P01-10 from Acris Antibodies
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Sarcospan / SSPN - H00008082-P01-25 from Acris Antibodies
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SSPN fusion protein - ag14526 from Proteintech Group
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SSPN fusion protein - ag14539 from Proteintech Group
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SSPN fusion protein - Ag24511 from Proteintech Group
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Recombinant Snurportin 1 (SNUPN1) - RPC863Hu01 from Cloud-clone
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Sarcospan / SSPN (transcript variant 1) - TP309123 from Acris Antibodies
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Sarcospan / SSPN (transcript variant 2) - TP327888 from Acris Antibodies
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SSPN-Blocking-Peptide-N-term - BP20496a from Abgent, a WuXi AppTec company
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SSPN Peptide, Human - M34GP15204H from Creative Peptides
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SSPN Recombinant Protein Antigen - NBP2-56991PEP from Novus Biologicals
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Sarcospan (SSPN), Recombinant Protein - MBS7030517 from MyBioSource
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