Gene Symbol | SSPN |
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Entrez Gene | 8082 |
Alt Symbol | DAGA5, KRAG, NSPN, SPN1, SPN2 |
Species | Human |
Gene Type | protein-coding |
Description | sarcospan |
Other Description | K-ras oncogene-associated protein|Kras oncogene-associated|kirsten-ras-associated protein|microspan|nanospan|sarcospan (Kras oncogene-associated gene) |
Swissprots | Q14714 B3KS67 |
Accessions | EAW96532 Q14714 AF016028 AAC61660 AK092925 BAG52629 AK304667 BAG65442 AK314353 BAG36988 AL136756 CAB66690 AM392675 CAL37553 AM392714 CAL37592 BC041929 BC062299 AAH62299 BP341300 CA419006 DA073350 DQ897666 ABI78937 EU433933 ACA09756 X89105 CAA61479 XM_011520853 XP_011519155 XM_011520854 XP_011519156 XM_011520855 XP_011519157 NM_001135823 NP_001129295 NM_005086 NP_005077 |
Function | Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane, sarcolemma {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Also found in myotendinous junctions and in the postsynaptic membrane of neuromuscular junctions. {ECO:0000250}. |
Tissue Specificity | Isoform 1 is expressed exclusively in heart and skeletal muscle. Isoform 2 is expressed in heart, skeletal muscle, thymus, prostate, testis, ovary, small intestine, colon and spleen. |
Sarcospan (E-2) - sc-393187 from Santa Cruz Biotechnology
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Sarcospan (P-20) - sc-30502 from Santa Cruz Biotechnology
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Sarcospan (H-50) - sc-50447 from Santa Cruz Biotechnology
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Sarcospan (C-20) - sc-16760 from Santa Cruz Biotechnology
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Anti-SSPN antibody - ab67584 from Abcam
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Anti-SSPN antibody - ab88784 from Abcam
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Anti-SSPN antibody - ab168664 from Abcam
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Anti-SSPN antibody [EPR15515] - ab186730 from Abcam
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Anti-SSPN / Sarcospan Antibody (aa144-193) - LS-C111107 from LifeSpan Bioscience
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Anti-SSPN / Sarcospan Antibody (aa6-34) - LS-C203966 from LifeSpan Bioscience
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SSPN Antibody - NBP1-59207 from Novus Biologicals
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SSPN Antibody - H00008082-B02 from Novus Biologicals
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SSPN Antibody - H00008082-B02P from Novus Biologicals
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SSPN Antibody - H00008082-D01P from Novus Biologicals
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SSPN Antibody - H00008082-D01 from Novus Biologicals
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Anti-SSPN antibody produced in rabbit - SAB1411461 from Sigma-Aldrich
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Anti-SSPN antibody produced in mouse - SAB1400310 from Sigma-Aldrich
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Anti-SSPN antibody produced in rabbit - SAB2102308 from Sigma-Aldrich
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SSPN antibody - middle region (ARP46567_P050) - ARP46567_P050 from Aviva Systems Biology
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SSPN-Antibody-N-term - AP20496a from Abgent, a WuXi AppTec company
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SSPN-Antibody-N-term - AW5200 from Abgent, a WuXi AppTec company
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SSPN Antibody - N-terminal region (OAAB18019) - OAAB18019 from Aviva Systems Biology
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Sarcospan antibody - 70R-6112 from Fitzgerald
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SSPN Antibody - abx034867 from Abbexa
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Sarcospan / SSPN antibody - H00008082-B02 from Acris Antibodies
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