UPP2

Gene Symbol UPP2
Entrez Gene 151531
Alt Symbol UDRPASE2, UP2, UPASE2
Species Human
Gene Type protein-coding
Description uridine phosphorylase 2
Other Description UPase 2|liver-specific uridine phosphorylase|urdPase 2|uridine phosphorylase-2
Swissprots B3KV87 O95045
Accessions AAD12227 EAX11437 O95045 AA995921 AK122743 BAG53699 AW771260 AY225131 AAO61681 BC033529 AAH33529 HG494776 HQ447870 ADQ32354 XM_005246359 XP_005246416 XR_922880 XR_922881 NM_001135098 NP_001128570 NM_173355 NP_775491
Function Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
Tissue Specificity Predominantly expressed in kidney. {ECO:0000269|PubMed:12849978}.
Top Pathways Drug metabolism - other enzymes, Pyrimidine metabolism

UPase 2 (Y-18) - sc-324474 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-UPP2 antibody - ab108049 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-UPP2 antibody (ab108049) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

Anti-UP2 / UPP2 Antibody (aa217-244) - LS-C160449 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UPP2 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-UP2 / UPP2 Antibody (aa217-244, AP) - LS-C242471 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UP2 / UPP2 Antibody (aa217-244, Biotin) - LS-C242474 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UP2 / UPP2 Antibody (aa217-244, APC) - LS-C242472 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UP2 / UPP2 Antibody (aa217-244, FITC) - LS-C242475 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UP2 / UPP2 Antibody (aa217-244, PE) - LS-C242476 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UP2 / UPP2 Antibody (aa217-244, Azide-free, HRP) - LS-C247198 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UP2 / UPP2 Antibody (aa217-244) - LS-C326210 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UP2 / UPP2 Antibody (aa200-249) - LS-C135220 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UPP2 antibody LS-C135220 Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml.

UPP2 Antibody - NBP2-20814 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UPP2 Antibody [NBP2-20814] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa 10% SDS PAGE gel, diluted at 1:3000.

UPP2 Antibody - H00151531-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: UPP2 Antibody [H00151531-B01P] - Analysis of UPP2 expression in transfected 293T cell line by UPP2 polyclonal antibody. Lane 1: UPP2 transfected lysate(34.87 KDa). Lane 2: Non-transfected lysate.

Anti-UPP2 (41-55) antibody produced in rabbit - SAB1103448 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human UPP2 was separated on SDS-PAGE, blotted with Anti-UPP2 (41-55) (<B>Cat. No. SAB1103448</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500<BR/>2. Antibody dilution 1:500 + UPP2 immunizing peptide (human, 41-55)

Anti-UPP2 (7-20) antibody produced in rabbit - SAB1103447 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human UPP2 was separated on SDS-PAGE, blotted with Anti-UPP2 (7-20) (<B>Cat. No. SAB1103447</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500<BR/>2. Antibody dilution 1:500 + UPP2 immunizing peptide (human, 7-20)

Anti-UPP2 antibody produced in rabbit - HPA035225 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UPP2: <B>Cat. No. HPA035225</B>: Immunohistochemical staining of human vagina shows moderate cytoplasmic positivity in squamous epithelial cells.

Anti-UPP2 antibody produced in rabbit - HPA035226 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UPP2: <B>Cat. No. HPA035226</B>: Immunohistochemical staining of human kidney shows moderate cytoplasmic, membranous and nuclear positivity in cells in tubules.

UPP2 Antibody - C-terminal region (OAAB01015) - OAAB01015 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

UPP2-Antibody-C-term - AP10995b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
UPP2 Antibody (C-term) (Cat. #AP10995b) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the UPP2 antibody detected the UPP2 protein (arrow).

Upp2 antibody - 70R-8803 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Uridine phosphorylase 2 (UPP2) (C-term) antibody - AP54478PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UPP2 antibody (C-term) (AP54478PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UPP2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Uridine phosphorylase 2 (UPP2) antibody - H00151531-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of UPP2 expression in transfected 293T cell line (H00151531-T01) by UPP2 MaxPab polyclonal antibody. Lane 1: UPP2 transfected lysate(34.87 KDa). Lane 2: Non-transfected lysate.

UPP2 antibody - 12964-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

UPP2, Polyclonal Antibody - MBS6001440 from MyBioSource

Prices $550.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

UPP2 - MBS272292 from MyBioSource

Prices $360.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa 10% SDS PAGE diluted at 1:3000
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