UPP2

Gene Symbol	UPP2
Entrez Gene	151531
Alt Symbol	UDRPASE2, UP2, UPASE2
Species	Human
Gene Type	protein-coding
Description	uridine phosphorylase 2
Other Description	UPase 2|liver-specific uridine phosphorylase|urdPase 2|uridine phosphorylase-2
Swissprots	B3KV87 O95045
Accessions	AAD12227 EAX11437 O95045 AA995921 AK122743 BAG53699 AW771260 AY225131 AAO61681 BC033529 AAH33529 HG494776 HQ447870 ADQ32354 XM_005246359 XP_005246416 XR_922880 XR_922881 NM_001135098 NP_001128570 NM_173355 NP_775491
Function	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
Tissue Specificity	Predominantly expressed in kidney. {ECO:0000269|PubMed:12849978}.
Top Pathways	Drug metabolism - other enzymes, Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UPP2 full length protein - ab165629 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human UPP2 Protein - H00151531-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

UPP2-Antibody-C-term-Blocking-peptide - BP10995b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Upp2 Blocking Peptide - 33R-8746 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Uridine phosphorylase 2 (UPP2) - H00151531-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Uridine phosphorylase 2 (UPP2) - H00151531-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

UPP2 fusion protein - Ag3619 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

UPP2 fusion protein - ag14860 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human UPP2, GST-tagged - UPP2-3604H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Uridine phosphorylase 2(UPP2) - CSB-YP025660HU CSB-EP025660HU CSB-BP025660HU CSB-MP025660HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Uridine phosphorylase 2 (UPP2) (transcript variant 1) - TP307260 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

UPP2 Peptide, Human - M34GP17116H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more